Entity Details

Primary name Six3
Entity type gene
Source Source Link

Details

PrimaryID20473
RefseqGene
SymbolSix3
Namesine oculis-related homeobox 3
Chromosome17
Location17 55.42 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSIX3_MOUSE

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001222 transcription corepressor binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001654 eye development
GO:0002070 epithelial cell maturation
GO:0002088 lens development in camera-type eye
GO:0003404 optic vesicle morphogenesis
GO:0003677 DNA binding
GO:0005102 signaling receptor binding
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006606 protein import into nucleus
GO:0007420 brain development
GO:0008406 gonad development
GO:0009946 proximal/distal axis specification
GO:0014016 neuroblast differentiation
GO:0021536 diencephalon development
GO:0021537 telencephalon development
GO:0021797 forebrain anterior/posterior pattern specification
GO:0021798 forebrain dorsal/ventral pattern formation
GO:0021846 cell proliferation in forebrain
GO:0021978 telencephalon regionalization
GO:0021983 pituitary gland development
GO:0030178 negative regulation of Wnt signaling pathway
GO:0030878 thyroid gland development
GO:0035264 multicellular organism growth
GO:0042127 regulation of cell population proliferation
GO:0042826 histone deacetylase binding
GO:0043010 camera-type eye development
GO:0043565 sequence-specific DNA binding
GO:0045665 negative regulation of neuron differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048512 circadian behavior
GO:0060235 lens induction in camera-type eye
GO:0061074 regulation of neural retina development
GO:0070306 lens fiber cell differentiation
GO:0097402 neuroblast migration
GO:1901987 regulation of cell cycle phase transition
GO:1902692 regulation of neuroblast proliferation
GO:1902742 apoptotic process involved in development
GO:1990086 lens fiber cell apoptotic process
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000177 regulation of neural precursor cell proliferation

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
Six3Tle5BioGRID, IntAct12050133 details
Six3Tle4BioGRID, IntAct12050133 details
Six3Hdac2DIP17666527 details
Six3Eya1BioGRID16024294 details