Entity Details

Primary name Slit2
Entity type gene
Source Source Link

Details

PrimaryID20563
RefseqGene
SymbolSlit2
Nameslit guidance ligand 2
Chromosome5
Location5
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSLIT2_MOUSE

GO terms

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GOName
GO:0001656 metanephros development
GO:0001657 ureteric bud development
GO:0001701 in utero embryonic development
GO:0001822 kidney development
GO:0001933 negative regulation of protein phosphorylation
GO:0002042 cell migration involved in sprouting angiogenesis
GO:0002689 negative regulation of leukocyte chemotaxis
GO:0003180 aortic valve morphogenesis
GO:0003184 pulmonary valve morphogenesis
GO:0005095 GTPase inhibitor activity
GO:0005102 signaling receptor binding
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007409 axonogenesis
GO:0007411 axon guidance
GO:0008045 motor neuron axon guidance
GO:0008201 heparin binding
GO:0008285 negative regulation of cell population proliferation
GO:0009986 cell surface
GO:0010593 negative regulation of lamellipodium assembly
GO:0010596 negative regulation of endothelial cell migration
GO:0010629 negative regulation of gene expression
GO:0014912 negative regulation of smooth muscle cell migration
GO:0021772 olfactory bulb development
GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration
GO:0021972 corticospinal neuron axon guidance through spinal cord
GO:0022029 telencephalon cell migration
GO:0030308 negative regulation of cell growth
GO:0030336 negative regulation of cell migration
GO:0030517 negative regulation of axon extension
GO:0030837 negative regulation of actin filament polymerization
GO:0031290 retinal ganglion cell axon guidance
GO:0033563 dorsal/ventral axon guidance
GO:0035385 Roundabout signaling pathway
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043116 negative regulation of vascular permeability
GO:0043237 laminin-1 binding
GO:0043394 proteoglycan binding
GO:0043395 heparan sulfate proteoglycan binding
GO:0045499 chemorepellent activity
GO:0048495 Roundabout binding
GO:0048754 branching morphogenesis of an epithelial tube
GO:0048812 neuron projection morphogenesis
GO:0048846 axon extension involved in axon guidance
GO:0050728 negative regulation of inflammatory response
GO:0050919 negative chemotaxis
GO:0050929 induction of negative chemotaxis
GO:0051058 negative regulation of small GTPase mediated signal transduction
GO:0060412 ventricular septum morphogenesis
GO:0060603 mammary gland duct morphogenesis
GO:0060763 mammary duct terminal end bud growth
GO:0062023 collagen-containing extracellular matrix
GO:0070100 negative regulation of chemokine-mediated signaling pathway
GO:0071504 cellular response to heparin
GO:0071672 negative regulation of smooth muscle cell chemotaxis
GO:0071676 negative regulation of mononuclear cell migration
GO:0090024 negative regulation of neutrophil chemotaxis
GO:0090027 negative regulation of monocyte chemotaxis
GO:0090260 negative regulation of retinal ganglion cell axon guidance
GO:0090288 negative regulation of cellular response to growth factor stimulus
GO:0098609 cell-cell adhesion

Diseases

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Interactions

6 interactions