Entity Details

Primary name PDK3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ922H2
EntryNamePDK3_MOUSE
FullName[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length415
SequenceStatuscomplete
DateCreated2005-03-15
DateModified2021-06-02

Ontological Relatives

GenesPdk3

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0005524 ATP binding
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006006 glucose metabolic process
GO:0006468 protein phosphorylation
GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010906 regulation of glucose metabolic process
GO:0018105 peptidyl-serine phosphorylation
GO:0035357 peroxisome proliferator activated receptor signaling pathway
GO:0071333 cellular response to glucose stimulus
GO:0071398 cellular response to fatty acid
GO:0097411 hypoxia-inducible factor-1alpha signaling pathway
GO:2000377 regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR003594 Histidine kinase/HSP90-like ATPaseDomainDomain
IPR005467 Histidine kinase domainDomainDomain
IPR018955 Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminalDomainDomain
IPR036784 Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamilyFamilyHomologous superfamily
IPR036890 Histidine kinase/HSP90-like ATPase superfamilyFamilyHomologous superfamily
IPR039028 PDK/BCKDK protein kinaseFamilyFamily

Diseases

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Interactions

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