Entity Details

Primary name Sorl1
Entity type gene
Source Source Link

Details

PrimaryID20660
RefseqGene
SymbolSorl1
Namesortilin-related receptor, LDLR class A repeats-containing
Chromosome9
Location9
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSORL_MOUSE

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001540 amyloid-beta binding
GO:0002024 diet induced thermogenesis
GO:0004888 transmembrane signaling receptor activity
GO:0005615 extracellular space
GO:0005641 nuclear envelope lumen
GO:0005768 endosome
GO:0005769 early endosome
GO:0005771 multivesicular body
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0006605 protein targeting
GO:0006622 protein targeting to lysosome
GO:0006892 post-Golgi vesicle-mediated transport
GO:0006898 receptor-mediated endocytosis
GO:0007218 neuropeptide signaling pathway
GO:0009986 cell surface
GO:0010897 negative regulation of triglyceride catabolic process
GO:0014910 regulation of smooth muscle cell migration
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016477 cell migration
GO:0030169 low-density lipoprotein particle binding
GO:0030514 negative regulation of BMP signaling pathway
GO:0030658 transport vesicle membrane
GO:0031267 small GTPase binding
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031901 early endosome membrane
GO:0031985 Golgi cisterna
GO:0032091 negative regulation of protein binding
GO:0032585 multivesicular body membrane
GO:0034067 protein localization to Golgi apparatus
GO:0038020 insulin receptor recycling
GO:0042923 neuropeptide binding
GO:0043025 neuronal cell body
GO:0043407 negative regulation of MAP kinase activity
GO:0045053 protein retention in Golgi apparatus
GO:0045732 positive regulation of protein catabolic process
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0050768 negative regulation of neurogenesis
GO:0051604 protein maturation
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
GO:0070863 positive regulation of protein exit from endoplasmic reticulum
GO:0097356 perinucleolar compartment
GO:1900168 positive regulation of glial cell-derived neurotrophic factor production
GO:1901215 negative regulation of neuron death
GO:1902430 negative regulation of amyloid-beta formation
GO:1902771 positive regulation of choline O-acetyltransferase activity
GO:1902948 negative regulation of tau-protein kinase activity
GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport
GO:1902955 positive regulation of early endosome to recycling endosome transport
GO:1902960 negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902963 negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902966 positive regulation of protein localization to early endosome
GO:1902997 negative regulation of neurofibrillary tangle assembly
GO:1904179 positive regulation of adipose tissue development
GO:1990845 adaptive thermogenesis
GO:2001137 positive regulation of endocytic recycling

Diseases

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Interactions

5 interactions