Entity Details

Primary name Sos1
Entity type gene
Source Source Link

Details

PrimaryID20662
RefseqGene
SymbolSos1
NameSOS Ras/Rac guanine nucleotide exchange factor 1
Chromosome17
Location17 50.67 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSOS1_MOUSE

GO terms

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GOName
GO:0001782 B cell homeostasis
GO:0001942 hair follicle development
GO:0002260 lymphocyte homeostasis
GO:0003007 heart morphogenesis
GO:0003209 cardiac atrium morphogenesis
GO:0003344 pericardium morphogenesis
GO:0003677 DNA binding
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0007265 Ras protein signal transduction
GO:0007296 vitellogenesis
GO:0014069 postsynaptic density
GO:0017124 SH3 domain binding
GO:0033081 regulation of T cell differentiation in thymus
GO:0035264 multicellular organism growth
GO:0042129 regulation of T cell proliferation
GO:0043025 neuronal cell body
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
GO:0046579 positive regulation of Ras protein signal transduction
GO:0046982 protein heterodimerization activity
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048514 blood vessel morphogenesis
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0060021 roof of mouth development
GO:0061029 eyelid development in camera-type eye
GO:0061384 heart trabecula morphogenesis
GO:1904693 midbrain morphogenesis
GO:2000973 regulation of pro-B cell differentiation

Diseases

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Interactions

51 interactions

InteractorPartnerSourcesPublicationsLink
Sos1Ubr1IntAct15102471 details
Sos1GRB2BioGRID, DIP, MINT, UniProt16906159 8940013 9368064 9569023 details
Sos1PRKD1BioGRID30631038 details
Sos1Abi1BioGRID, IntAct11003655 32325033 details
Sos1Plcg1BioGRID, IntAct15953601 32325033 details
Sos1Shc1BioGRID, MINT17673906 8479540 9013573 details
Sos1Grb2BioGRID, IntAct, MINT, UniProt10373493 23452850 32325033 8479540 9569023 details
Sos1EGFRMINT8479540 details
Sos1ITSN1MINT18539136 details
Sos1NOSTRINMINT22751148 details
Sos1Cops3BioGRID, MINT30631038 details
Sos1CrklBioGRID32325033 8978305 details
Sos1Spry1BioGRID11585837 details
Sos1Spry2BioGRID11585837 16339969 details
Sos1Spry4BioGRID16339969 details
Sos1Spry3BioGRID16339969 details
Sos1EgfrBioGRID23027125 8479540 details
Sos1Eps8BioGRID12515821 32325033 details
Sos1NgfrBioGRID9368064 details
Sos1Cops7aBioGRID30631038 details
Sos1PtprcIntAct8570203 details
Sos1Cd22IntAct10373493 details
Sos1RetIntAct19914172 details
Sos1LRRK1IntAct20697350 details
Sos1EporUniProt9569023 details
Sos1LatIntAct24584089 details
Sos1LATDIP16906159 details
Sos1Sh3kbp1BioGRID32325033 details
Sos1CblBioGRID32325033 details
Sos1Arhgap26BioGRID32325033 details
Sos1Arhgap35BioGRID32325033 details
Sos1Cd2apBioGRID32325033 details
Sos1Dock1BioGRID32325033 details
Sos1Eps8l1BioGRID32325033 details
Sos1GnasBioGRID32325033 details
Sos1Klhl7BioGRID32325033 details
Sos1LpxnBioGRID32325033 details
Sos1NostrinBioGRID32325033 details
Sos1Pdlim5BioGRID32325033 details
Sos1Prickle2BioGRID32325033 details
Sos1Rapgef4BioGRID32325033 details
Sos1Rasgef1bBioGRID32325033 details
Sos1Arhgap42BioGRID32325033 details
Sos1Csf1rBioGRID32325033 details
Sos1Dab2ipBioGRID32325033 details
Sos1DmdBioGRID32325033 details
Sos1Fcho2BioGRID32325033 details
Sos1Gpr31bBioGRID32325033 details
Sos1Prickle1BioGRID32325033 details
Sos1Ptpn11BioGRID32325033 details
Sos1Strip2BioGRID32325033 details