Entity Details

Primary name Src
Entity type gene
Source Source Link

Details

PrimaryID20779
RefseqGene
SymbolSrc
NameRous sarcoma oncogene
Chromosome2
Location2 78.35 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSRC_MOUSE

GO terms

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GOName
GO:0001545 primary ovarian follicle growth
GO:0001819 positive regulation of cytokine production
GO:0002102 podosome
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005102 signaling receptor binding
GO:0005158 insulin receptor binding
GO:0005178 integrin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005764 lysosome
GO:0005770 late endosome
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0005925 focal adhesion
GO:0006468 protein phosphorylation
GO:0007049 cell cycle
GO:0007155 cell adhesion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0008022 protein C-terminus binding
GO:0008283 cell population proliferation
GO:0009612 response to mechanical stimulus
GO:0009615 response to virus
GO:0010447 response to acidic pH
GO:0010628 positive regulation of gene expression
GO:0010632 regulation of epithelial cell migration
GO:0010634 positive regulation of epithelial cell migration
GO:0010907 positive regulation of glucose metabolic process
GO:0010954 positive regulation of protein processing
GO:0014069 postsynaptic density
GO:0014911 positive regulation of smooth muscle cell migration
GO:0016004 phospholipase activator activity
GO:0016020 membrane
GO:0016301 kinase activity
GO:0016310 phosphorylation
GO:0016477 cell migration
GO:0018105 peptidyl-serine phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019899 enzyme binding
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0020037 heme binding
GO:0022407 regulation of cell-cell adhesion
GO:0030054 cell junction
GO:0030154 cell differentiation
GO:0030331 estrogen receptor binding
GO:0030900 forebrain development
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031625 ubiquitin protein ligase binding
GO:0031648 protein destabilization
GO:0031667 response to nutrient levels
GO:0031954 positive regulation of protein autophosphorylation
GO:0032148 activation of protein kinase B activity
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0032587 ruffle membrane
GO:0032869 cellular response to insulin stimulus
GO:0033146 regulation of intracellular estrogen receptor signaling pathway
GO:0034332 adherens junction organization
GO:0034446 substrate adhesion-dependent cell spreading
GO:0034614 cellular response to reactive oxygen species
GO:0035306 positive regulation of dephosphorylation
GO:0035556 intracellular signal transduction
GO:0036035 osteoclast development
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0038083 peptidyl-tyrosine autophosphorylation
GO:0042169 SH2 domain binding
GO:0042476 odontogenesis
GO:0042493 response to drug
GO:0043005 neuron projection
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043149 stress fiber assembly
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043274 phospholipase binding
GO:0043393 regulation of protein binding
GO:0043406 positive regulation of MAP kinase activity
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0044325 transmembrane transporter binding
GO:0044877 protein-containing complex binding
GO:0045056 transcytosis
GO:0045087 innate immune response
GO:0045453 bone resorption
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045747 positive regulation of Notch signaling pathway
GO:0045785 positive regulation of cell adhesion
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0046777 protein autophosphorylation
GO:0046875 ephrin receptor binding
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048041 focal adhesion assembly
GO:0048471 perinuclear region of cytoplasm
GO:0048477 oogenesis
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050839 cell adhesion molecule binding
GO:0050847 progesterone receptor signaling pathway
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0051219 phosphoprotein binding
GO:0051222 positive regulation of protein transport
GO:0051385 response to mineralocorticoid
GO:0051602 response to electrical stimulus
GO:0051895 negative regulation of focal adhesion assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0051902 negative regulation of mitochondrial depolarization
GO:0051974 negative regulation of telomerase activity
GO:0060065 uterus development
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0060491 regulation of cell projection assembly
GO:0060576 intestinal epithelial cell development
GO:0070102 interleukin-6-mediated signaling pathway
GO:0070301 cellular response to hydrogen peroxide
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070555 response to interleukin-1
GO:0070700 BMP receptor binding
GO:0070851 growth factor receptor binding
GO:0071222 cellular response to lipopolysaccharide
GO:0071253 connexin binding
GO:0071375 cellular response to peptide hormone stimulus
GO:0071393 cellular response to progesterone stimulus
GO:0071398 cellular response to fatty acid
GO:0071456 cellular response to hypoxia
GO:0071498 cellular response to fluid shear stress
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0071803 positive regulation of podosome assembly
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:0086098 angiotensin-activated signaling pathway involved in heart process
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0097110 scaffold protein binding
GO:0098609 cell-cell adhesion
GO:0098962 regulation of postsynaptic neurotransmitter receptor activity
GO:0098978 glutamatergic synapse
GO:0099091 postsynaptic specialization, intracellular component
GO:1900182 positive regulation of protein localization to nucleus
GO:1902533 positive regulation of intracellular signal transduction
GO:2000386 positive regulation of ovarian follicle development
GO:2000394 positive regulation of lamellipodium morphogenesis
GO:2000573 positive regulation of DNA biosynthetic process
GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway
GO:2000641 regulation of early endosome to late endosome transport
GO:2000811 negative regulation of anoikis
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway
GO:2001286 regulation of caveolin-mediated endocytosis

Diseases

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Interactions

109 interactions

InteractorPartnerSourcesPublicationsLink
SrcPrkceBioGRID, IntAct11139474 11834516 details
SrcPTK2MINT18560762 21266176 details
SrcPtpraMINT7518772 details
SrcROR1IntAct22439932 details
SrcITGB3mbinfo14593208 details
SrcPXNmbinfo16478788 details
SrcPxnBioGRID, mbinfo14636584 16478788 details
SrcFrs2IntAct23452850 details
SrcHK1IntAct28054552 details
SrcHK2IntAct28054552 details
SrcTrpc1DIP16407161 details
SrcTRPC3DIP16407161 details
SrcTrpc6DIP16407161 details
SrcTrpc5DIP16407161 details
SrcTrpc2DIP16407161 details
SrcTrpc4DIP16407161 details
SrcCblBioGRID, DIP11804588 17420256 22138575 32325033 8635998 8849724 9013636 details
SrcDvl2BioGRID19920076 details
SrcKhdrbs1BioGRID10844001 15890643 details
SrcEno1BioGRID14739300 9013636 details
SrcSrcBioGRID10684249 17135401 details
SrcCsn2BioGRID10684249 details
SrcPik3c2aBioGRID10684249 details
SrcEfsBioGRID8647432 details
SrcPrkacaBioGRID11804588 details
SrcEnahBioGRID8861907 details
SrcPtk2BioGRID, MINT10362356 10931187 16966330 18233957 32325033 details
SrcGrin2bBioGRID, IntAct10862698 16635246 details
SrcDok2MINT15831486 details
SrcPdcd6ipMINT15557335 details
SrcCsf1IntAct16267818 details
SrcEphb2IntAct16298995 details
SrcHtr4MINT19661922 details
SrcWasMolecular Connections18289379 details
SrcCSF1RMINT7730365 details
SrcRetMINT22732841 details
SrcMap1lc3bBioGRID, DIP, MINT22138575 22732841 details
SrcCsf1rBioGRID, DIP17420256 18840695 32325033 details
SrcItgb3DIP18840695 details
SrcAkt1BioGRID, DIP19122674 details
SrcGja1BioGRID, DIP21282606 32325033 details
SrcSkp2BioGRID20596523 details
SrcS1pr1BioGRID21102457 details
SrcJak2BioGRID21102457 details
SrcPtk2bBioGRID11274221 14739300 details
SrcInpp5dBioGRID16601135 details
SrcDiaph1BioGRID18194650 details
SrcKdrBioGRID16966330 18194650 details
SrcEgfrBioGRID11274221 details
SrcCav3BioGRID14600260 8663016 details
SrcDab1BioGRID15062102 details
SrcGab1BioGRID12808090 details
SrcEsr1BioGRID17921256 details
SrcShc1BioGRID15716419 details
SrcShc2BioGRID15716419 details
SrcShc3BioGRID15716419 details
SrcAtxn2BioGRID18602463 details
SrcArrb1BioGRID19122674 32325033 details
SrcArrb2BioGRID19122674 details
SrcBcar1BioGRID11038351 details
SrcItga2BioGRID11038351 details
SrcEp300BioGRID26695438 details
SrcHcn2BioGRID16079136 32325033 details
SrcGrin1BioGRID, IntAct, MINT10862698 16635246 details
SrcYwhabIntAct16635246 details
SrcSrcin1BioGRID, IntAct19146815 32325033 details
SrcInsrBioGRID, DIP19122674 details
SrcShank3BioGRID, IntAct28671696 details
SrcAgap2BioGRID, IntAct28706196 details
SrcAfdnBioGRID32325033 details
SrcAnxa1BioGRID32325033 details
SrcEpb41l3BioGRID32325033 details
SrcGsnBioGRID32325033 details
SrcMapk15BioGRID32325033 details
SrcPsmb9BioGRID32325033 details
SrcPtpn23BioGRID32325033 details
SrcArid1aBioGRID32325033 details
SrcCkap5BioGRID32325033 details
SrcSyn1BioGRID32325033 details
SrcTiam2BioGRID32325033 details
SrcUsp8BioGRID32325033 details
SrcActn1BioGRID32325033 details
SrcArhgap1BioGRID32325033 details
SrcArr3BioGRID32325033 details
SrcAsap1BioGRID32325033 details
SrcAsap2BioGRID32325033 details
SrcCar3BioGRID32325033 details
SrcCastBioGRID32325033 details
SrcCtnnb1BioGRID32325033 details
SrcCtslBioGRID32325033 details
SrcDgkzBioGRID32325033 details
SrcEpha4BioGRID32325033 details
SrcGnsBioGRID32325033 details
SrcGrk2BioGRID32325033 details
SrcHspa2BioGRID32325033 details
SrcMap2BioGRID32325033 details
SrcMical1BioGRID32325033 details
SrcNansBioGRID32325033 details
SrcOstf1BioGRID32325033 details
SrcPlcg1BioGRID32325033 details
SrcPtpn11BioGRID32325033 details
SrcPtpn2BioGRID32325033 details
SrcSnx17BioGRID32325033 details
SrcGfapBioGRID32325033 details
SrcNmt1BioGRID32325033 details
SrcShroom2BioGRID32325033 details
SrcTns3BioGRID32325033 details
SrcTpt1BioGRID32325033 details
SrcTubBioGRID32325033 details