Entity Details

Primary name Stx1a
Entity type gene
Source Source Link

Details

PrimaryID20907
RefseqGene
SymbolStx1a
Namesyntaxin 1A (brain)
Chromosome5
Location5
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSTX1A_MOUSE

GO terms

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GOName
GO:0000149 SNARE binding
GO:0001669 acrosomal vesicle
GO:0001956 positive regulation of neurotransmitter secretion
GO:0005484 SNAP receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006886 intracellular protein transport
GO:0006887 exocytosis
GO:0006906 vesicle fusion
GO:0008021 synaptic vesicle
GO:0008076 voltage-gated potassium channel complex
GO:0009629 response to gravity
GO:0010701 positive regulation of norepinephrine secretion
GO:0010807 regulation of synaptic vesicle priming
GO:0012505 endomembrane system
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016079 synaptic vesicle exocytosis
GO:0016081 synaptic vesicle docking
GO:0016925 protein sumoylation
GO:0017022 myosin binding
GO:0017156 calcium-ion regulated exocytosis
GO:0017157 regulation of exocytosis
GO:0019855 calcium channel inhibitor activity
GO:0019869 chloride channel inhibitor activity
GO:0019900 kinase binding
GO:0019904 protein domain specific binding
GO:0030073 insulin secretion
GO:0030141 secretory granule
GO:0030285 integral component of synaptic vesicle membrane
GO:0030424 axon
GO:0030672 synaptic vesicle membrane
GO:0030674 protein-macromolecule adaptor activity
GO:0031201 SNARE complex
GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane
GO:0031965 nuclear membrane
GO:0032028 myosin head/neck binding
GO:0032940 secretion by cell
GO:0032991 protein-containing complex
GO:0033605 positive regulation of catecholamine secretion
GO:0035493 SNARE complex assembly
GO:0042641 actomyosin
GO:0042734 presynaptic membrane
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043008 ATP-dependent protein binding
GO:0043229 intracellular organelle
GO:0044325 transmembrane transporter binding
GO:0044877 protein-containing complex binding
GO:0045055 regulated exocytosis
GO:0045921 positive regulation of exocytosis
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0046879 hormone secretion
GO:0047485 protein N-terminus binding
GO:0048278 vesicle docking
GO:0048306 calcium-dependent protein binding
GO:0048488 synaptic vesicle endocytosis
GO:0048787 presynaptic active zone membrane
GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex
GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex
GO:0072657 protein localization to membrane
GO:0098815 modulation of excitatory postsynaptic potential
GO:0098978 glutamatergic synapse
GO:0099056 integral component of presynaptic membrane
GO:2000463 positive regulation of excitatory postsynaptic potential

Diseases

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Interactions

36 interactions

InteractorPartnerSourcesPublicationsLink
Stx1aVamp2BioGRID, DIP, MINT16269331 18385322 20114047 20798282 21151134 26280336 26437117 32325033 details
Stx1aSnap25BioGRID, DIP, MINT16269331 17283335 18385322 20114047 20798282 21151134 24705552 32325033 details
Stx1aStx1aBioGRID21151134 details
Stx1aSyt2MINT16642042 details
Stx1aStxbp1BioGRID, MINT20114047 32325033 7890599 details
Stx1aRusc1UniProt22404429 details
Stx1aSec22bBioGRID, DIP24705552 32325033 details
Stx1aSncaBioGRID20798282 21151134 details
Stx1aSlc6a3BioGRID18617632 details
Stx1aCacna1dBioGRID10468580 details
Stx1aVps11BioGRID14623309 details
Stx1aVps18BioGRID14623309 details
Stx1aStxbp2BioGRID7890599 details
Stx1aNapaBioGRID18385322 32325033 details
Stx1aSeptin5BioGRID18385322 details
Stx1aYwhabIntAct16635246 details
Stx1aGrin1IntAct16635246 details
Stx1aGrin2bIntAct16635246 details
Stx1aChgaIntAct16369483 details
Stx1aCltcIntAct19562802 details
Stx1aKcnma1BioGRID, MINT20114047 details
Stx1aSNCABioGRID, IntAct18614564 details
Stx1aNsfIntAct21307259 details
Stx1aLRRK2IntAct21307259 24687852 details
Stx1aLrrk2IntAct24687852 details
Stx1aSnap23BioGRID, DIP24705552 details
Stx1aSnap29BioGRID, DIP24705552 32325033 details
Stx1aPpp1ccBioGRID17274640 details
Stx1aMaptBioGRID30068389 details
Stx1aCplx2BioGRID32325033 details
Stx1aCplx3BioGRID32325033 details
Stx1aCplx1BioGRID32325033 details
Stx1aNapbBioGRID32325033 details
Stx1aSnx4BioGRID32325033 details
Stx1aStx1bBioGRID32325033 details
Stx1aVamp1BioGRID32325033 details