Entity Details

Primary name Stxbp1
Entity type gene
Source Source Link

Details

PrimaryID20910
RefseqGene
SymbolStxbp1
Namesyntaxin binding protein 1
Chromosome2
Location2 22.09 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSTXB1_MOUSE

GO terms

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GOName
GO:0000149 SNARE binding
GO:0002576 platelet degranulation
GO:0003006 developmental process involved in reproduction
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0006886 intracellular protein transport
GO:0006887 exocytosis
GO:0006904 vesicle docking involved in exocytosis
GO:0007269 neurotransmitter secretion
GO:0007274 neuromuscular synaptic transmission
GO:0007412 axon target recognition
GO:0010807 regulation of synaptic vesicle priming
GO:0016082 synaptic vesicle priming
GO:0016188 synaptic vesicle maturation
GO:0016192 vesicle-mediated transport
GO:0017075 syntaxin-1 binding
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0019905 syntaxin binding
GO:0030141 secretory granule
GO:0030424 axon
GO:0031091 platelet alpha granule
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031338 regulation of vesicle fusion
GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane
GO:0032229 negative regulation of synaptic transmission, GABAergic
GO:0032355 response to estradiol
GO:0032991 protein-containing complex
GO:0035493 SNARE complex assembly
GO:0042802 identical protein binding
GO:0043209 myelin sheath
GO:0043274 phospholipase binding
GO:0043306 positive regulation of mast cell degranulation
GO:0043524 negative regulation of neuron apoptotic process
GO:0045335 phagocytic vesicle
GO:0045921 positive regulation of exocytosis
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0047485 protein N-terminus binding
GO:0048471 perinuclear region of cytoplasm
GO:0048787 presynaptic active zone membrane
GO:0050821 protein stabilization
GO:0060292 long-term synaptic depression
GO:0070527 platelet aggregation
GO:0071346 cellular response to interferon-gamma
GO:0072659 protein localization to plasma membrane
GO:0098793 presynapse
GO:0098794 postsynapse
GO:0098891 extrinsic component of presynaptic active zone membrane
GO:0098978 glutamatergic synapse
GO:0099525 presynaptic dense core vesicle exocytosis
GO:0106022 positive regulation of vesicle docking
GO:1903296 positive regulation of glutamate secretion, neurotransmission
GO:2000367 regulation of acrosomal vesicle exocytosis

Diseases

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Interactions

41 interactions

InteractorPartnerSourcesPublicationsLink
Stxbp1MTNR1ABioGRID26514267 details
Stxbp1MTNR1BBioGRID26514267 details
Stxbp1Stx1aBioGRID, MINT20114047 32325033 7890599 details
Stxbp1Grm4DIP19822743 details
Stxbp1Grm7DIP19822743 details
Stxbp1Aph1aBioGRID15146195 details
Stxbp1Aph1bBioGRID15146195 details
Stxbp1PrnpBioGRID15146195 details
Stxbp1Stx4aBioGRID7890599 details
Stxbp1Ppp1r9bBioGRID28634551 30562941 details
Stxbp1YwhabIntAct16635246 details
Stxbp1Grin2bIntAct16635246 details
Stxbp1CALM1BioGRID, IntAct16512683 details
Stxbp1CALM2IntAct16512683 details
Stxbp1CALM3IntAct16512683 details
Stxbp1YwhazIntAct19562802 details
Stxbp1Dlg4IntAct19455133 details
Stxbp1Kcnma1BioGRID, MINT20114047 details
Stxbp1SNCABioGRID, IntAct18614564 details
Stxbp1CaskIntAct19022416 details
Stxbp1Rpgrip1lIntAct21565611 details
Stxbp1LRRK2IntAct24687852 details
Stxbp1Lrrk2IntAct24687852 details
Stxbp1HTTIntAct17500595 details
Stxbp1Agap2BioGRID, IntAct28706196 details
Stxbp1PPT1MINT30918483 details
Stxbp1Atxn1BioGRID30457570 details
Stxbp1Dnm1BioGRID32325033 details
Stxbp1Negr1BioGRID32325033 details
Stxbp1Cdk5BioGRID32325033 details
Stxbp1Doc2aBioGRID32325033 details
Stxbp1NefhBioGRID32325033 details
Stxbp1NeflBioGRID32325033 details
Stxbp1NefmBioGRID32325033 details
Stxbp1NsfBioGRID32325033 details
Stxbp1PrkcbBioGRID32325033 details
Stxbp1PrkcgBioGRID32325033 details
Stxbp1Apba1BioGRID32325033 details
Stxbp1Tuba4aBioGRID32325033 details
Stxbp1Tubb2aBioGRID32325033 details
Stxbp1Vamp2BioGRID32325033 details