Entity Details

Primary name Syk
Entity type gene
Source Source Link

Details

PrimaryID20963
RefseqGene
SymbolSyk
Namespleen tyrosine kinase
Chromosome13
Location13 27.41 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsKSYK_MOUSE

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001525 angiogenesis
GO:0001784 phosphotyrosine residue binding
GO:0001819 positive regulation of cytokine production
GO:0001820 serotonin secretion
GO:0001945 lymph vessel development
GO:0002092 positive regulation of receptor internalization
GO:0002250 adaptive immune response
GO:0002281 macrophage activation involved in immune response
GO:0002283 neutrophil activation involved in immune response
GO:0002366 leukocyte activation involved in immune response
GO:0002554 serotonin secretion by platelet
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005102 signaling receptor binding
GO:0005178 integrin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006606 protein import into nucleus
GO:0007159 leukocyte cell-cell adhesion
GO:0007166 cell surface receptor signaling pathway
GO:0007167 enzyme linked receptor protein signaling pathway
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0007257 obsolete activation of JUN kinase activity
GO:0010543 regulation of platelet activation
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway
GO:0016170 interleukin-15 receptor binding
GO:0018105 peptidyl-serine phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019370 leukotriene biosynthetic process
GO:0019815 B cell receptor complex
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0019904 protein domain specific binding
GO:0030154 cell differentiation
GO:0030593 neutrophil chemotaxis
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031334 positive regulation of protein-containing complex assembly
GO:0031623 receptor internalization
GO:0031625 ubiquitin protein ligase binding
GO:0032009 early phagosome
GO:0032481 positive regulation of type I interferon production
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032733 positive regulation of interleukin-10 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032752 positive regulation of interleukin-3 production
GO:0032753 positive regulation of interleukin-4 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032928 regulation of superoxide anion generation
GO:0032930 positive regulation of superoxide anion generation
GO:0032991 protein-containing complex
GO:0033630 positive regulation of cell adhesion mediated by integrin
GO:0035325 Toll-like receptor binding
GO:0035556 intracellular signal transduction
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway
GO:0038156 interleukin-3-mediated signaling pathway
GO:0042101 T cell receptor complex
GO:0042169 SH2 domain binding
GO:0042742 defense response to bacterium
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043306 positive regulation of mast cell degranulation
GO:0043313 regulation of neutrophil degranulation
GO:0043366 beta selection
GO:0045087 innate immune response
GO:0045579 positive regulation of B cell differentiation
GO:0045588 positive regulation of gamma-delta T cell differentiation
GO:0045780 positive regulation of bone resorption
GO:0046638 positive regulation of alpha-beta T cell differentiation
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0046777 protein autophosphorylation
GO:0048514 blood vessel morphogenesis
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050764 regulation of phagocytosis
GO:0050776 regulation of immune response
GO:0050850 positive regulation of calcium-mediated signaling
GO:0050853 B cell receptor signaling pathway
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0051712 positive regulation of killing of cells of other organism
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0071226 cellular response to molecule of fungal origin
GO:0071404 cellular response to low-density lipoprotein particle stimulus
GO:0071639 positive regulation of monocyte chemotactic protein-1 production
GO:0090237 regulation of arachidonic acid secretion
GO:0090330 regulation of platelet aggregation
GO:0097110 scaffold protein binding
GO:0120162 positive regulation of cold-induced thermogenesis

Diseases

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