Entity Details

Primary name Tap2
Entity type gene
Source Source Link

Details

PrimaryID21355
RefseqGene
SymbolTap2
Nametransporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Chromosome17
Location17 17.98 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-09-04
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsTAP2_MOUSE

GO terms

Show/Hide Table
GOName
GO:0000166 nucleotide binding
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002237 response to molecule of bacterial origin
GO:0002250 adaptive immune response
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I
GO:0005524 ATP binding
GO:0005783 endoplasmic reticulum
GO:0015031 protein transport
GO:0015433 ABC-type peptide antigen transporter activity
GO:0015440 ABC-type peptide transporter activity
GO:0015833 peptide transport
GO:0016021 integral component of membrane
GO:0016607 nuclear speck
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0023029 MHC class Ib protein binding
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0042270 protection from natural killer cell mediated cytotoxicity
GO:0042288 MHC class I protein binding
GO:0042605 peptide antigen binding
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042824 MHC class I peptide loading complex
GO:0042825 TAP complex
GO:0043231 intracellular membrane-bounded organelle
GO:0043531 ADP binding
GO:0044877 protein-containing complex binding
GO:0046872 metal ion binding
GO:0046967 cytosol to endoplasmic reticulum transport
GO:0046968 peptide antigen transport
GO:0046978 TAP1 binding
GO:0046979 TAP2 binding
GO:0046980 tapasin binding
GO:0055085 transmembrane transport
GO:0065003 protein-containing complex assembly

Diseases

Show/Hide Table

Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
Tap2TapbpBioGRID9973410 details
Tap2Abcf1InnateDB23263557 details
Tap2LatIntAct24584089 details
Tap2Fancd2BioGRID28378742 details
Tap2CfdBioGRID30550785 details
Tap2Fndc5BioGRID30550785 details