Entity Details

Primary name Tbx5
Entity type gene
Source Source Link

Details

PrimaryID21388
RefseqGene
SymbolTbx5
NameT-box 5
Chromosome5
Location5 60.42 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsTBX5_MOUSE

GO terms

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GOName
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001708 cell fate specification
GO:0002009 morphogenesis of an epithelium
GO:0003166 bundle of His development
GO:0003167 atrioventricular bundle cell differentiation
GO:0003181 atrioventricular valve morphogenesis
GO:0003197 endocardial cushion development
GO:0003218 cardiac left ventricle formation
GO:0003229 ventricular cardiac muscle tissue development
GO:0003281 ventricular septum development
GO:0003283 atrial septum development
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007267 cell-cell signaling
GO:0007389 pattern specification process
GO:0007507 heart development
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0030324 lung development
GO:0030326 embryonic limb morphogenesis
GO:0030336 negative regulation of cell migration
GO:0032991 protein-containing complex
GO:0032993 protein-DNA complex
GO:0035115 embryonic forelimb morphogenesis
GO:0035136 forelimb morphogenesis
GO:0043565 sequence-specific DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048513 animal organ development
GO:0051891 positive regulation of cardioblast differentiation
GO:0055007 cardiac muscle cell differentiation
GO:0060039 pericardium development
GO:0060044 negative regulation of cardiac muscle cell proliferation
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060290 transdifferentiation
GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization
GO:0060413 atrial septum morphogenesis
GO:0060928 atrioventricular node cell development
GO:0060929 atrioventricular node cell fate commitment
GO:0072513 positive regulation of secondary heart field cardioblast proliferation
GO:0086019 cell-cell signaling involved in cardiac conduction
GO:0086054 bundle of His cell to Purkinje myocyte communication by electrical coupling
GO:1903598 positive regulation of gap junction assembly
GO:1903781 positive regulation of cardiac conduction

Diseases

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Interactions

64 interactions

InteractorPartnerSourcesPublicationsLink
Tbx5Smarcd3DIP17210915 details
Tbx5Nkx2-5BioGRID11572777 details
Tbx5Chd4bhf-ucl26859351 details
Tbx5CHD4bhf-ucl26859351 details
Tbx5Hand2IntAct28469241 details
Tbx5Smarca4BioGRID15525990 details
Tbx5Sall4BioGRID16380715 details
Tbx5Fbxo25BioGRID25725482 details
Tbx5UbcBioGRID25725482 details
Tbx5Hdac2bhf-ucl26859351 details
Tbx5Nostrinbhf-ucl26859351 details
Tbx5Smarcc2bhf-ucl26859351 details
Tbx5Thoc5bhf-ucl26859351 details
Tbx5Zfp512bhf-ucl26859351 details
Tbx5Zfp326bhf-ucl26859351 details
Tbx5Trim25bhf-ucl26859351 details
Tbx5Tbx5bhf-ucl26859351 details
Tbx5Stag1bhf-ucl26859351 details
Tbx5Rbm15bhf-ucl26859351 details
Tbx5Nfiabhf-ucl26859351 details
Tbx5Iws1bhf-ucl26859351 details
Tbx5Htatsf1bhf-ucl26859351 details
Tbx5Sltmbhf-ucl26859351 details
Tbx5Riox1bhf-ucl26859351 details
Tbx5Exosc10bhf-ucl26859351 details
Tbx5Safbbhf-ucl26859351 details
Tbx5Zfxbhf-ucl26859351 details
Tbx5Tmpobhf-ucl26859351 details
Tbx5Scaf1bhf-ucl26859351 details
Tbx5Rbm14bhf-ucl26859351 details
Tbx5Cavin1bhf-ucl26859351 details
Tbx5Mtdhbhf-ucl26859351 details
Tbx5Khdrbs1bhf-ucl26859351 details
Tbx5Trim28bhf-ucl26859351 details
Tbx5Top1bhf-ucl26859351 details
Tbx5Tardbpbhf-ucl26859351 details
Tbx5Taf6bhf-ucl26859351 details
Tbx5Taf5bhf-ucl26859351 details
Tbx5Taf4bbhf-ucl26859351 details
Tbx5Supt16bhf-ucl26859351 details
Tbx5Ssrp1bhf-ucl26859351 details
Tbx5Snw1bhf-ucl26859351 details
Tbx5Smarca5bhf-ucl26859351 details
Tbx5Ruvbl2bhf-ucl26859351 details
Tbx5Rbbp5bhf-ucl26859351 details
Tbx5Rbbp4bhf-ucl26859351 details
Tbx5Prpf6bhf-ucl26859351 details
Tbx5Pelp1bhf-ucl26859351 details
Tbx5Nclbhf-ucl26859351 details
Tbx5Mybbp1abhf-ucl26859351 details
Tbx5Mecp2bhf-ucl26859351 details
Tbx5Larp7bhf-ucl26859351 details
Tbx5Ilkbhf-ucl26859351 details
Tbx5Gatad2bbhf-ucl26859351 details
Tbx5Gatad2abhf-ucl26859351 details
Tbx5Eif4a3bhf-ucl26859351 details
Tbx5Ctnnd1bhf-ucl26859351 details
Tbx5Ctcfbhf-ucl26859351 details
Tbx5Csnk2a1bhf-ucl26859351 details
Tbx5Cdk9bhf-ucl26859351 details
Tbx5Cdc5lbhf-ucl26859351 details
Tbx5Ccar1bhf-ucl26859351 details
Tbx5Actl6abhf-ucl26859351 details
Tbx5MTA1bhf-ucl26859351 details