Entity Details

Primary name Agap2
Entity type gene
Source Source Link

Details

PrimaryID216439
RefseqGene
SymbolAgap2
NameArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Chromosome10
Location10
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-05-05
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsAGAP2_MOUSE

GO terms

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GOName
GO:0003924 GTPase activity
GO:0005096 GTPase activator activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016197 endosomal transport
GO:0019901 protein kinase binding
GO:0030036 actin cytoskeleton organization
GO:0030295 protein kinase activator activity
GO:0033601 positive regulation of mammary gland epithelial cell proliferation
GO:0035014 phosphatidylinositol 3-kinase regulator activity
GO:0042177 negative regulation of protein catabolic process
GO:0043066 negative regulation of apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0045860 positive regulation of protein kinase activity
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0046872 metal ion binding
GO:0060749 mammary gland alveolus development
GO:0090543 Flemming body
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Diseases

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Interactions

179 interactions

InteractorPartnerSourcesPublicationsLink
Agap2Stat5aBioGRID, MINT20075866 details
Agap2InsrMINT21720388 details
Agap2Unc5bIntAct18469807 details
Agap2DccIntAct18469807 details
Agap2Grip1MINT21847098 details
Agap2Ppp1r9bBioGRID, IntAct28634551 28706196 30562941 details
Agap2PrlrBioGRID20075866 details
Agap2YwhabIntAct16635246 details
Agap2SNCABioGRID, IntAct18614564 details
Agap2Cnksr2BioGRID, IntAct28671696 28706196 details
Agap2Cyfip1BioGRID, IntAct28671696 28706196 details
Agap2Homer1BioGRID, IntAct28671696 28706196 32325033 details
Agap2Syngap1BioGRID, IntAct27507650 28671696 28706196 details
Agap2Pde4dipBioGRID, IntAct28671696 details
Agap2TnikBioGRID, IntAct28671696 28706196 details
Agap2Dlg4BioGRID, IntAct27507650 28671696 28706196 details
Agap2Dlgap1BioGRID, IntAct27507650 28671696 28706196 details
Agap2Shank3BioGRID, IntAct27507650 28671696 28706196 details
Agap2Sorbs2BioGRID, IntAct28706196 details
Agap2Wasf1BioGRID, IntAct28706196 details
Agap2TrioBioGRID, IntAct28706196 details
Agap2Syne1BioGRID, IntAct28706196 details
Agap2SrcBioGRID, IntAct28706196 details
Agap2Sorbs1BioGRID, IntAct28706196 details
Agap2Shank2BioGRID, IntAct28706196 details
Agap2Shank1BioGRID, IntAct28706196 details
Agap2Septin7BioGRID, IntAct28706196 details
Agap2Septin5BioGRID, IntAct28706196 details
Agap2Rasal1BioGRID, IntAct28706196 details
Agap2Ralgapa1BioGRID, IntAct28706196 details
Agap2Ptk2BioGRID, IntAct28706196 details
Agap2PrkcgBioGRID, IntAct28706196 details
Agap2PrkceBioGRID, IntAct28706196 details
Agap2PrkcbBioGRID, IntAct28706196 details
Agap2PrkacbBioGRID, IntAct28706196 details
Agap2PrkacaBioGRID, IntAct28706196 details
Agap2Ppp3caBioGRID, IntAct28706196 details
Agap2Ppp1cbBioGRID, IntAct28706196 details
Agap2Ppp1caBioGRID, IntAct28706196 details
Agap2NrcamBioGRID, IntAct28706196 details
Agap2Nf1BioGRID, IntAct28706196 details
Agap2Nedd4BioGRID, IntAct28706196 details
Agap2Nckap1BioGRID, IntAct28706196 details
Agap2Ncam2BioGRID, IntAct28706196 details
Agap2NbeaBioGRID, IntAct28706196 details
Agap2Mapk3BioGRID, IntAct28706196 details
Agap2Mapk1BioGRID, IntAct28706196 details
Agap2Map2k1BioGRID, IntAct28706196 details
Agap2Lrrc7BioGRID, IntAct28706196 details
Agap2KalrnBioGRID, IntAct28706196 details
Agap2Iqsec3BioGRID, IntAct28706196 details
Agap2Iqsec2BioGRID, IntAct28706196 details
Agap2Iqsec1BioGRID, IntAct28706196 details
Agap2Iqgap2BioGRID, IntAct28706196 details
Agap2Iqgap1BioGRID, IntAct28706196 details
Agap2GsnBioGRID, IntAct28706196 details
Agap2Gsk3bBioGRID, IntAct28706196 details
Agap2Grm3BioGRID, IntAct28706196 details
Agap2Grm2BioGRID, IntAct28706196 details
Agap2Grm1BioGRID, IntAct28706196 details
Agap2Grin2bBioGRID, IntAct28706196 details
Agap2Grin2aBioGRID, IntAct28706196 details
Agap2Grin1BioGRID, IntAct28706196 details
Agap2Gnb2BioGRID, IntAct28706196 details
Agap2Gnb1BioGRID, IntAct28706196 details
Agap2GnazBioGRID, IntAct28706196 details
Agap2GnasBioGRID, IntAct28706196 details
Agap2GnaqBioGRID, IntAct28706196 details
Agap2Gnao1BioGRID, IntAct28706196 details
Agap2Gnai1BioGRID, IntAct28706196 details
Agap2Gna13BioGRID, IntAct28706196 details
Agap2Gdi2BioGRID, IntAct28706196 details
Agap2Epb41l2BioGRID, IntAct28706196 details
Agap2Epb41l1BioGRID, IntAct28706196 32325033 details
Agap2Dlgap2BioGRID, IntAct28706196 details
Agap2Dbn1BioGRID, IntAct28706196 details
Agap2Cyfip2BioGRID, IntAct28706196 details
Agap2Camk2gBioGRID, IntAct28706196 details
Agap2Camk2dBioGRID, IntAct28706196 details
Agap2Camk2bBioGRID, IntAct28706196 details
Agap2Camk2aBioGRID, IntAct28706196 details
Agap2Arhgef18BioGRID, IntAct28706196 details
Agap2Arhgap39BioGRID, IntAct28706196 details
Agap2Appl1BioGRID, IntAct28706196 details
Agap2Ap2a1BioGRID, IntAct28706196 details
Agap2Ank3BioGRID, IntAct28706196 details
Agap2Dync1i1BioGRID, IntAct28706196 details
Agap2Ppm1eBioGRID, IntAct28706196 details
Agap2Dync1li1BioGRID, IntAct28706196 details
Agap2Pitpnm1BioGRID, IntAct28706196 details
Agap2Luzp1BioGRID, IntAct28706196 details
Agap2TnrBioGRID, IntAct28706196 details
Agap2Sptbn1BioGRID, IntAct28706196 details
Agap2PcnaBioGRID, IntAct28706196 details
Agap2NefmBioGRID, IntAct28706196 details
Agap2NeflBioGRID, IntAct28706196 details
Agap2InaBioGRID, IntAct28706196 details
Agap2Gna11BioGRID, IntAct28706196 details
Agap2GlulBioGRID, IntAct28706196 details
Agap2NumblBioGRID, IntAct28706196 details
Agap2Usp9xBioGRID, IntAct28706196 details
Agap2Csnk2a2BioGRID, IntAct28706196 details
Agap2Anxa2BioGRID, IntAct28706196 details
Agap2Atp1b1BioGRID, IntAct28706196 details
Agap2Ank2BioGRID, IntAct28706196 details
Agap2Prmt8BioGRID, IntAct28706196 details
Agap2Ak5BioGRID, IntAct28706196 details
Agap2Phactr1BioGRID, IntAct28706196 details
Agap2Pip5kl1BioGRID, IntAct28706196 details
Agap2Sik3BioGRID, IntAct28706196 details
Agap2Camkk2BioGRID, IntAct28706196 details
Agap2Ppfia2BioGRID, IntAct28706196 details
Agap2CltcBioGRID, IntAct28706196 details
Agap2Rims2BioGRID, IntAct28706196 details
Agap2Rims1BioGRID, IntAct28706196 details
Agap2Srgap3BioGRID, IntAct28706196 details
Agap2Cep170bBioGRID, IntAct28706196 details
Agap2Trp53bp2BioGRID, IntAct28706196 details
Agap2Actn1BioGRID, IntAct28706196 details
Agap2Srcin1BioGRID, IntAct28706196 details
Agap2Arpc1aBioGRID, IntAct28706196 details
Agap2Ube4bBioGRID, IntAct28706196 details
Agap2Ppp2r1aBioGRID, IntAct28706196 details
Agap2Anks1bBioGRID, IntAct28706196 details
Agap2Atad3aBioGRID, IntAct28706196 details
Agap2Ap2b1BioGRID, IntAct28706196 details
Agap2Tln2BioGRID, IntAct28706196 details
Agap2Rapgef4BioGRID, IntAct28706196 details
Agap2Dab2ipBioGRID, IntAct28706196 details
Agap2Nmral1BioGRID, IntAct28706196 details
Agap2Kctd16BioGRID, IntAct28706196 details
Agap2Actn4BioGRID, IntAct28706196 details
Agap2Pqbp1BioGRID, IntAct28706196 details
Agap2SacsBioGRID, IntAct28706196 details
Agap2Grm5BioGRID, IntAct28706196 details
Agap2Dpysl2BioGRID, IntAct28706196 details
Agap2PcloBioGRID, IntAct28706196 details
Agap2NcdnBioGRID, IntAct28706196 details
Agap2Asap1BioGRID, IntAct28706196 details
Agap2StrnBioGRID, IntAct28706196 details
Agap2Dclk1BioGRID, IntAct28706196 details
Agap2Pkp1BioGRID, IntAct28706196 details
Agap2Map1aBioGRID, IntAct28706196 details
Agap2Map6BioGRID, IntAct28706196 details
Agap2Prag1BioGRID, IntAct28706196 details
Agap2GphnBioGRID, IntAct28706196 details
Agap2Pkn2BioGRID, IntAct28706196 details
Agap2EnahBioGRID, IntAct28706196 details
Agap2NptnBioGRID, IntAct28706196 details
Agap2Crmp1BioGRID, IntAct28706196 details
Agap2Dnm1BioGRID, IntAct28706196 details
Agap2Stxbp1BioGRID, IntAct28706196 details
Agap2Ppp3cbBioGRID, IntAct28706196 details
Agap2Cdc42BioGRID, IntAct28706196 details
Agap2Myo5aBioGRID, IntAct28706196 details
Agap2Cacnb3BioGRID, IntAct28706196 details
Agap2Dync1h1BioGRID, IntAct28706196 details
Agap2Epb41l3BioGRID, IntAct28706196 details
Agap2Ap2a2BioGRID, IntAct28706196 details
Agap2Cdk5BioGRID, IntAct28706196 details
Agap2Lnx2BioGRID27889896 details
Agap2Ap1b1BioGRID28706196 details
Agap2Dlg1BioGRID28706196 details
Agap2Dlg2BioGRID28706196 details
Agap2Dlg3BioGRID28706196 details
Agap2Dlgap3BioGRID28706196 details
Agap2Dlgap4BioGRID28706196 details
Agap2Git1BioGRID28706196 details
Agap2Gria1BioGRID28706196 details
Agap2Homer2BioGRID28706196 details
Agap2Mapk10BioGRID28706196 details
Agap2Mink1BioGRID28706196 details
Agap2Nlgn1BioGRID28706196 details
Agap2Nlgn3BioGRID28706196 details
Agap2Prkar2bBioGRID28706196 details
Agap2PrkcaBioGRID28706196 details
Agap2Ptk2bBioGRID28706196 details
Agap2Rgs14BioGRID29518331 details
Agap2Slc6a4BioGRID32581705 details