Entity Details

Primary name Timp3
Entity type gene
Source Source Link

Details

PrimaryID21859
RefseqGene
SymbolTimp3
Nametissue inhibitor of metalloproteinase 3
Chromosome10
Location10 42.83 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsTIMP3_MOUSE

GO terms

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GOName
GO:0002020 protease binding
GO:0004857 enzyme inhibitor activity
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0008191 metalloendopeptidase inhibitor activity
GO:0008270 zinc ion binding
GO:0009725 response to hormone
GO:0010033 response to organic substance
GO:0010951 negative regulation of endopeptidase activity
GO:0031012 extracellular matrix
GO:0034097 response to cytokine
GO:0045861 negative regulation of proteolysis
GO:0051045 negative regulation of membrane protein ectodomain proteolysis
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071310 cellular response to organic substance
GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway
GO:1904684 negative regulation of metalloendopeptidase activity

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
Timp3Fancd2BioGRID28378742 details