Entity Details

Primary name Tjp1
Entity type gene
Source Source Link

Details

PrimaryID21872
RefseqGene
SymbolTjp1
Nametight junction protein 1
Chromosome7
Location7 35.02 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsZO1_MOUSE

GO terms

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GOName
GO:0001825 blastocyst formation
GO:0005516 calmodulin binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005921 gap junction
GO:0005923 bicellular tight junction
GO:0007605 sensory perception of sound
GO:0008022 protein C-terminus binding
GO:0008284 positive regulation of cell population proliferation
GO:0009986 cell surface
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016327 apicolateral plasma membrane
GO:0019904 protein domain specific binding
GO:0030054 cell junction
GO:0030335 positive regulation of cell migration
GO:0031032 actomyosin structure organization
GO:0031674 I band
GO:0032496 response to lipopolysaccharide
GO:0032991 protein-containing complex
GO:0034334 adherens junction maintenance
GO:0042493 response to drug
GO:0043066 negative regulation of apoptotic process
GO:0043116 negative regulation of vascular permeability
GO:0043296 apical junction complex
GO:0045177 apical part of cell
GO:0045216 cell-cell junction organization
GO:0045471 response to ethanol
GO:0046581 intercellular canaliculus
GO:0050839 cell adhesion molecule binding
GO:0051493 regulation of cytoskeleton organization
GO:0051497 negative regulation of stress fiber assembly
GO:0070160 tight junction
GO:0071000 response to magnetism
GO:0071253 connexin binding
GO:0071333 cellular response to glucose stimulus
GO:0071896 protein localization to adherens junction
GO:0090557 establishment of endothelial intestinal barrier
GO:0098609 cell-cell adhesion
GO:0150105 protein localization to cell-cell junction
GO:1901888 regulation of cell junction assembly
GO:1902396 protein localization to bicellular tight junction
GO:1903672 positive regulation of sprouting angiogenesis
GO:1905605 positive regulation of blood-brain barrier permeability
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin
GO:2000250 negative regulation of actin cytoskeleton reorganization
GO:2000810 regulation of bicellular tight junction assembly

Diseases

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Interactions

45 interactions

InteractorPartnerSourcesPublicationsLink
Tjp1CGNBioGRID, UniProt12023291 details
Tjp1VclIntAct24413171 details
Tjp1OCLNBioGRID7798316 details
Tjp1Grin1BioGRID, IntAct10862698 16635246 details
Tjp1Cldn1MINT10601346 11689568 details
Tjp1Cldn2MINT10601346 details
Tjp1Cldn3MINT10601346 details
Tjp1Cldn5MINT10601346 details
Tjp1Cldn6MINT10601346 details
Tjp1Cldn4BioGRID, MINT10601346 32325033 details
Tjp1Cldn7MINT10601346 details
Tjp1Cldn8MINT10601346 details
Tjp1MpdzMINT11689568 details
Tjp1Gja1BioGRID, DIP, IntAct, MINT16045494 21282606 24413171 32325033 details
Tjp1Gjb6MINT16045494 details
Tjp1Ybx3MINT16045494 details
Tjp1Actn4BioGRID, IntAct16944923 details
Tjp1PTPN1MINT18515860 details
Tjp1OclnDIP19841260 details
Tjp1Grin2bMINT10862698 details
Tjp1YwhabIntAct16635246 details
Tjp1WRAP73UniProt26675238 details
Tjp1Cnksr2BioGRID, IntAct28671696 32325033 details
Tjp1Mycbp2BioGRID, IntAct28671696 details
Tjp1TnikBioGRID, IntAct28671696 details
Tjp1DlstIntAct29128334 details
Tjp1Cav3IntAct24952909 details
Tjp1CFTRBioGRID17110338 details
Tjp1EedBioGRID24457600 details
Tjp1HnrnpkBioGRID26336360 details
Tjp1Brsk2BioGRID32325033 details
Tjp1Magi1BioGRID32325033 details
Tjp1ActbBioGRID32325033 details
Tjp1Actn1BioGRID32325033 details
Tjp1AfdnBioGRID32325033 details
Tjp1Mtm1BioGRID32325033 details
Tjp1Ctnna1BioGRID32325033 details
Tjp1Gna11BioGRID32325033 details
Tjp1Tubb4aBioGRID32325033 details
Tjp1Tubb5BioGRID32325033 details
Tjp1Clca1BioGRID32325033 details
Tjp1Rbm26BioGRID32325033 details
Tjp1Wfs1BioGRID32325033 details
Tjp1CfdBioGRID30550785 details
Tjp1Fndc5BioGRID30550785 details