Entity Details

Primary name Tnfrsf1a
Entity type gene
Source Source Link

Details

PrimaryID21937
RefseqGene
SymbolTnfrsf1a
Nametumor necrosis factor receptor superfamily, member 1a
Chromosome6
Location6 59.32 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-25
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsTNR1A_MOUSE

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0002020 protease binding
GO:0003176 aortic valve development
GO:0003177 pulmonary valve development
GO:0003332 negative regulation of extracellular matrix constituent secretion
GO:0005031 tumor necrosis factor-activated receptor activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006693 prostaglandin metabolic process
GO:0006952 defense response
GO:0006954 inflammatory response
GO:0007166 cell surface receptor signaling pathway
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009986 cell surface
GO:0010614 negative regulation of cardiac muscle hypertrophy
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016021 integral component of membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0030424 axon
GO:0032715 negative regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032991 protein-containing complex
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0042307 positive regulation of protein import into nucleus
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042742 defense response to bacterium
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043120 tumor necrosis factor binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043235 receptor complex
GO:0043525 positive regulation of neuron apoptotic process
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0045202 synapse
GO:0045766 positive regulation of angiogenesis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050728 negative regulation of inflammatory response
GO:0050729 positive regulation of inflammatory response
GO:0071260 cellular response to mechanical stimulus
GO:0072659 protein localization to plasma membrane
GO:1902339 positive regulation of apoptotic process involved in morphogenesis
GO:1903140 regulation of establishment of endothelial barrier

Diseases

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Interactions

39 interactions

InteractorPartnerSourcesPublicationsLink
Tnfrsf1aTRADDBioGRID, HPIDb, IntAct11374864 7758105 details
Tnfrsf1aSlc2a1IntAct15102471 details
Tnfrsf1aEhmt2IntAct15102471 details
Tnfrsf1aOdc1IntAct15102471 details
Tnfrsf1aFbln2IntAct15102471 details
Tnfrsf1aAgtrapIntAct15102471 details
Tnfrsf1aVapaIntAct15102471 details
Tnfrsf1aSlc9a1IntAct15102471 details
Tnfrsf1aSonIntAct15102471 details
Tnfrsf1aSlc39a7IntAct15102471 details
Tnfrsf1aSec61bIntAct15102471 details
Tnfrsf1aRnf111IntAct15102471 details
Tnfrsf1aTnfBioGRID, IntAct11448951 18022363 18621737 24469399 29203883 29891719 30420664 details
Tnfrsf1aTNFBioGRID, DIP11448951 26649818 details
Tnfrsf1aBabam2BioGRID9737713 details
Tnfrsf1aMapk1BioGRID15865443 details
Tnfrsf1aCanxMINT16680093 details
Tnfrsf1aErn1MINT16680093 details
Tnfrsf1aRipk1BioGRID, DIP, IntAct, MINT16547522 16680093 18022363 18719121 23602765 29203883 29891719 30209212 details
Tnfrsf1aKarsIntAct16291755 details
Tnfrsf1aUbbDIP26649818 details
Tnfrsf1aUbcDIP26649818 details
Tnfrsf1aRps27aDIP26649818 details
Tnfrsf1aUba52DIP26649818 details
Tnfrsf1aFaddDIP26649818 details
Tnfrsf1aIrak1BioGRID18562480 details
Tnfrsf1aIkbkbBioGRID16547522 29891719 32325033 details
Tnfrsf1aIkbkgBioGRID16547522 details
Tnfrsf1aFEM1BBioGRID10542291 details
Tnfrsf1aSykBioGRID16291755 details
Tnfrsf1aTnfaip3BioGRID23602765 29203883 29891719 30209212 32325033 details
Tnfrsf1aRnf31BioGRID24461064 29203883 32325033 details
Tnfrsf1aTnip1BioGRID29203883 details
Tnfrsf1aSharpinBioGRID29203883 details
Tnfrsf1aCybaBioGRID19641494 details
Tnfrsf1aBirc2IntAct18022363 details
Tnfrsf1aTraf2DIP, HPIDb, IntAct11374864 18022363 18719121 details
Tnfrsf1aTraddDIP19641494 details
Tnfrsf1aRfkBioGRID, DIP19641494 32325033 details