Entity Details

Primary name Tnks
Entity type gene
Source Source Link

Details

PrimaryID21951
RefseqGene
SymbolTnks
Nametankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Chromosome8
Location8 21.16 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsTNKS1_MOUSE

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000209 protein polyubiquitination
GO:0000781 chromosome, telomeric region
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0006471 protein ADP-ribosylation
GO:0008270 zinc ion binding
GO:0015031 protein transport
GO:0016055 Wnt signaling pathway
GO:0016604 nuclear body
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0031670 cellular response to nutrient
GO:0031965 nuclear membrane
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0042393 histone binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051028 mRNA transport
GO:0051225 spindle assembly
GO:0051301 cell division
GO:0051973 positive regulation of telomerase activity
GO:0070198 protein localization to chromosome, telomeric region
GO:0070212 protein poly-ADP-ribosylation
GO:0070213 protein auto-ADP-ribosylation
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0097431 mitotic spindle pole
GO:1904355 positive regulation of telomere capping
GO:1904357 negative regulation of telomere maintenance via telomere lengthening
GO:1904743 negative regulation of telomeric DNA binding
GO:1904908 negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric
GO:1990404 protein ADP-ribosylase activity

Diseases

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Interactions

23 interactions

InteractorPartnerSourcesPublicationsLink
TnksRNF146DIP25327252 details
TnksKif3aBioGRID22473005 details
TnksTNKS1BP1BioGRID, IntAct26496610 details
TnksABRAXAS2BioGRID, IntAct26496610 details
TnksNUMA1BioGRID, IntAct26496610 details
TnksHERC2BioGRID, IntAct26496610 details
TnksZMYND8BioGRID, IntAct26496610 details
TnksDMAC2LBioGRID, IntAct26496610 details
TnksMRPL24BioGRID, IntAct26496610 details
TnksPSMD2BioGRID, IntAct26496610 details
TnksSLC39A10BioGRID, IntAct26496610 details
TnksTNKS2BioGRID, IntAct26496610 details
TnksZNF687BioGRID, IntAct26496610 details
TnksZNRD2BioGRID, IntAct26496610 details
TnksSBSNBioGRID, IntAct26496610 details
TnksSH3BP5BioGRID, IntAct26496610 details
TnksGMDSBioGRID, IntAct26496610 details
TnksSLX4BioGRID, IntAct26496610 details
TnksTsc1BioGRID, IntAct28671696 details
TnksHdac4BioGRID, MINT31040226 details
TnksSDC2BioGRID26496610 details
TnksSpg7BioGRID32325033 details
TnksWbp4BioGRID32325033 details