Entity Details

Primary name Traf3
Entity type gene
Source Source Link

Details

PrimaryID22031
RefseqGene
SymbolTraf3
NameTNF receptor-associated factor 3
Chromosome12
Location12 60.94 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsTRAF3_MOUSE

GO terms

Show/Hide Table
GOName
GO:0001817 regulation of cytokine production
GO:0002224 toll-like receptor signaling pathway
GO:0004842 ubiquitin-protein transferase activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005768 endosome
GO:0006915 apoptotic process
GO:0008063 Toll signaling pathway
GO:0008270 zinc ion binding
GO:0009898 cytoplasmic side of plasma membrane
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0030162 regulation of proteolysis
GO:0031625 ubiquitin protein ligase binding
GO:0031996 thioesterase binding
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032648 regulation of interferon-beta production
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035631 CD40 receptor complex
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response
GO:0046330 positive regulation of JNK cascade
GO:0050688 regulation of defense response to virus
GO:0070534 protein K63-linked ubiquitination

Diseases

Show/Hide Table

Interactions

47 interactions

InteractorPartnerSourcesPublicationsLink
Traf3Tnfrsf4IntAct9418902 details
Traf3Tnfrsf9IntAct9418902 details
Traf3Tnfrsf11aIntAct15102471 details
Traf3PTPN22IntAct23871208 details
Traf3Ticam1BioGRID, DIP16306936 16306937 19898473 details
Traf3Myd88BioGRID, DIP16306937 19898473 22011580 details
Traf3Birc3BioGRID18635759 details
Traf3Mysm1BioGRID26474655 details
Traf3MavsBioGRID, MINT16858409 25847972 32324863 details
Traf3UbbDIP, IntAct18083102 23334419 details
Traf3UbcDIP, IntAct18083102 23334419 details
Traf3Rps27aDIP, IntAct18083102 23334419 details
Traf3Uba52DIP, IntAct18083102 23334419 details
Traf3Traf2I2D20818435 details
Traf3TBK1DIP, IntAct16306936 27094905 details
Traf3EIF2AK2DIP16306936 details
Traf3IRAK1DIP16306936 details
Traf3IKBKEDIP16306936 details
Traf3OTUD7BDIP23334419 details
Traf3Cd40BioGRID, DIP18635759 23334419 25072696 details
Traf3Otud7bBioGRID, DIP23334419 details
Traf3Malt1IntAct19917778 details
Traf3TNFRSF19BioGRID10809768 details
Traf3Tlr4BioGRID19898473 details
Traf3Rnf41BioGRID19483718 details
Traf3Tnfrsf13cBioGRID21041452 details
Traf3Traf3ip2BioGRID22649194 details
Traf3SykBioGRID23962979 details
Traf3Nedd4BioGRID25072696 details
Traf3Ppp1r13bBioGRID25072696 details
Traf3Creb1BioGRID26755589 details
Traf3Traf6BioGRID26474655 details
Traf3Tbk1BioGRID26474655 32324863 details
Traf3Stub1BioGRID25792747 details
Traf3PycardBioGRID25847972 details
Traf3Stk38BioGRID28219902 details
Traf3Il17raBioGRID28219902 details
Traf3Trim24BioGRID32324863 details
Traf3LtbrBioGRID, DIP23334419 details
Traf3CD40BioGRID, DIP23334419 details
Traf3Dlg4BioGRID, IntAct27507650 28671696 details
Traf3Plxdc2BioGRID32325033 details
Traf3Sec63BioGRID32325033 details
Traf3Il1bBioGRID32325033 details
Traf3Rnf216BioGRID32325033 details
Traf3Tnfrsf17BioGRID32325033 details
Traf3Slc6a4BioGRID32581705 details