Entity Details

Primary name Plscr1
Entity type gene
Source Source Link

Details

PrimaryID22038
RefseqGene
SymbolPlscr1
Namephospholipid scramblase 1
Chromosome9
Location9
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-06-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPLS1_MOUSE

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001618 virus receptor activity
GO:0003677 DNA binding
GO:0004518 nuclease activity
GO:0005154 epidermal growth factor receptor binding
GO:0005509 calcium ion binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006659 phosphatidylserine biosynthetic process
GO:0006915 apoptotic process
GO:0006953 acute-phase response
GO:0006955 immune response
GO:0008270 zinc ion binding
GO:0010288 response to lead ion
GO:0010628 positive regulation of gene expression
GO:0017121 plasma membrane phospholipid scrambling
GO:0017124 SH3 domain binding
GO:0017128 phospholipid scramblase activity
GO:0019899 enzyme binding
GO:0030099 myeloid cell differentiation
GO:0032091 negative regulation of protein binding
GO:0032791 lead ion binding
GO:0033003 regulation of mast cell activation
GO:0035455 response to interferon-alpha
GO:0035456 response to interferon-beta
GO:0042609 CD4 receptor binding
GO:0043065 positive regulation of apoptotic process
GO:0045071 negative regulation of viral genome replication
GO:0045089 positive regulation of innate immune response
GO:0045121 membrane raft
GO:0045340 mercury ion binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048471 perinuclear region of cytoplasm
GO:0050765 negative regulation of phagocytosis
GO:0051607 defense response to virus
GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway
GO:0062023 collagen-containing extracellular matrix
GO:0070782 phosphatidylserine exposure on apoptotic cell surface
GO:0071222 cellular response to lipopolysaccharide
GO:0071345 cellular response to cytokine stimulus
GO:0097193 intrinsic apoptotic signaling pathway
GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1905820 positive regulation of chromosome separation
GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
Plscr1Rasd1BioGRID, IntAct21247419 details
Plscr1Trim59BioGRID29467473 details