Entity Details

Primary name Tsg101
Entity type gene
Source Source Link

Details

PrimaryID22088
RefseqGene
SymbolTsg101
Nametumor susceptibility gene 101
Chromosome7
Location7
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-04-03
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsTS101_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000813 ESCRT I complex
GO:0001558 regulation of cell growth
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006513 protein monoubiquitination
GO:0006858 extracellular transport
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity
GO:0008285 negative regulation of cell population proliferation
GO:0008333 endosome to lysosome transport
GO:0010008 endosome membrane
GO:0015031 protein transport
GO:0030154 cell differentiation
GO:0030216 keratinocyte differentiation
GO:0030374 nuclear receptor coactivator activity
GO:0031625 ubiquitin protein ligase binding
GO:0031901 early endosome membrane
GO:0031902 late endosome membrane
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0043405 regulation of MAP kinase activity
GO:0044877 protein-containing complex binding
GO:0046755 viral budding
GO:0046790 virion binding
GO:0048306 calcium-dependent protein binding
GO:0051301 cell division
GO:0070062 extracellular exosome
GO:0090543 Flemming body
GO:1902188 positive regulation of viral release from host cell
GO:1903543 positive regulation of exosomal secretion
GO:1903551 regulation of extracellular exosome assembly
GO:1903774 positive regulation of viral budding via host ESCRT complex
GO:1990182 exosomal secretion
GO:2000397 positive regulation of ubiquitin-dependent endocytosis

Diseases

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Interactions

56 interactions

InteractorPartnerSourcesPublicationsLink
Tsg101CDKN1AMINT11943869 details
Tsg101HgsBioGRID, MINT12802020 32325033 details
Tsg101Ppp1ccBioGRID, IntAct17274640 details
Tsg101Cep55IntAct20176808 details
Tsg101IkbkgBioGRID, IntAct20211142 details
Tsg101Tsg101BioGRID, IntAct20211142 details
Tsg101Nfe2BioGRID, IntAct20211142 details
Tsg101Gmcl1BioGRID12927808 details
Tsg101Mgrn1BioGRID19703557 details
Tsg101UbcBioGRID28190767 details
Tsg101LRSAM1IntAct28335037 details
Tsg101Gjc1BioGRID19210987 details
Tsg101Gja1BioGRID19210987 details
Tsg101Gjd3BioGRID19210987 details
Tsg101Gjb3BioGRID19210987 details
Tsg101SH3KBP1BioGRID21725061 details
Tsg101Ndfip1BioGRID23012657 details
Tsg101Sqstm1BioGRID31286822 details
Tsg101Pdcd6BioGRID, IntAct17889823 32325033 details
Tsg101RNF103-CHMP3IntAct26496610 details
Tsg101CHMP3BioGRID, IntAct26496610 details
Tsg101CYBRD1BioGRID, IntAct26496610 details
Tsg101CHMP2BBioGRID, IntAct26496610 details
Tsg101GPRC5ABioGRID, IntAct26496610 details
Tsg101CAV1BioGRID, IntAct26496610 details
Tsg101MVB12ABioGRID, IntAct26496610 details
Tsg101VPS37ABioGRID, IntAct26496610 details
Tsg101ERLIN1BioGRID, IntAct26496610 details
Tsg101FLOT2BioGRID, IntAct26496610 details
Tsg101UBAP1BioGRID, IntAct26496610 details
Tsg101IST1BioGRID, IntAct26496610 details
Tsg101VPS28BioGRID, IntAct26496610 details
Tsg101CHMP4BBioGRID, IntAct26496610 details
Tsg101VPS37BBioGRID, IntAct26496610 details
Tsg101CHMP5BioGRID, IntAct26496610 details
Tsg101VPS37CBioGRID26496610 details
Tsg101Eif4bBioGRID32325033 details
Tsg101Gga1BioGRID32325033 details
Tsg101Mvb12bBioGRID32325033 details
Tsg101Snf8BioGRID32325033 details
Tsg101Ddx6BioGRID32325033 details
Tsg101FasnBioGRID32325033 details
Tsg101Scamp3BioGRID32325033 details
Tsg101Vps37bBioGRID32325033 details
Tsg101Vps37cBioGRID32325033 details
Tsg101Acad8BioGRID32325033 details
Tsg101DlatBioGRID32325033 details
Tsg101FdpsBioGRID32325033 details
Tsg101Atxn2BioGRID32325033 details
Tsg101CopeBioGRID32325033 details
Tsg101Tom1BioGRID32325033 details
Tsg101Vps28BioGRID32325033 details
Tsg101Abcb6BioGRID32325033 details
Tsg101Birc2BioGRID32325033 details
Tsg101Dzip3BioGRID32325033 details
Tsg101PigqBioGRID32325033 details