Entity Details

Primary name Vhl
Entity type gene
Source Source Link

Details

PrimaryID22346
RefseqGene
SymbolVhl
Namevon Hippel-Lindau tumor suppressor
Chromosome6
Location6 52.81 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsVHL_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001525 angiogenesis
GO:0001666 response to hypoxia
GO:0003309 type B pancreatic cell differentiation
GO:0003310 pancreatic A cell differentiation
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005929 cilium
GO:0006355 regulation of transcription, DNA-templated
GO:0006582 melanin metabolic process
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0010468 regulation of gene expression
GO:0010498 proteasomal protein catabolic process
GO:0010629 negative regulation of gene expression
GO:0015031 protein transport
GO:0016020 membrane
GO:0016567 protein ubiquitination
GO:0019899 enzyme binding
GO:0030163 protein catabolic process
GO:0030182 neuron differentiation
GO:0030198 extracellular matrix organization
GO:0030891 VCB complex
GO:0031462 Cul2-RING ubiquitin ligase complex
GO:0042069 regulation of catecholamine metabolic process
GO:0043534 blood vessel endothelial cell migration
GO:0044877 protein-containing complex binding
GO:0045471 response to ethanol
GO:0045602 negative regulation of endothelial cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
GO:0048069 eye pigmentation
GO:0048593 camera-type eye morphogenesis
GO:0048877 homeostasis of number of retina cells
GO:0050679 positive regulation of epithelial cell proliferation
GO:0061072 iris morphogenesis
GO:0061073 ciliary body morphogenesis
GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070243 regulation of thymocyte apoptotic process
GO:0070244 negative regulation of thymocyte apoptotic process
GO:0098794 postsynapse
GO:0098978 glutamatergic synapse
GO:0099175 regulation of postsynapse organization
GO:0099576 regulation of protein catabolic process at postsynapse, modulating synaptic transmission
GO:1902072 negative regulation of hypoxia-inducible factor-1alpha signaling pathway
GO:1903827 regulation of cellular protein localization
GO:1990756 ubiquitin ligase-substrate adaptor activity
GO:2001233 regulation of apoptotic signaling pathway

Diseases

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