Entity Details

Primary name CAC1D_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ99246
EntryNameCAC1D_MOUSE
FullNameVoltage-dependent L-type calcium channel subunit alpha-1D
TaxID10090
Evidenceevidence at protein level
Length2179
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesCacna1d

GO terms

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GOName
GO:0005245 voltage-gated calcium channel activity
GO:0005262 calcium channel activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0006816 calcium ion transport
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007605 sensory perception of sound
GO:0008331 high voltage-gated calcium channel activity
GO:0009986 cell surface
GO:0016324 apical plasma membrane
GO:0019722 calcium-mediated signaling
GO:0030001 metal ion transport
GO:0030018 Z disc
GO:0030165 PDZ domain binding
GO:0030425 dendrite
GO:0030506 ankyrin binding
GO:0032590 dendrite membrane
GO:0032793 positive regulation of CREB transcription factor activity
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042383 sarcolemma
GO:0043025 neuronal cell body
GO:0045762 positive regulation of adenylate cyclase activity
GO:0046872 metal ion binding
GO:0051393 alpha-actinin binding
GO:0051924 regulation of calcium ion transport
GO:0051928 positive regulation of calcium ion transport
GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization
GO:0061337 cardiac conduction
GO:0070509 calcium ion import
GO:0070588 calcium ion transmembrane transport
GO:0086002 cardiac muscle cell action potential involved in contraction
GO:0086046 membrane depolarization during SA node cell action potential
GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
GO:0098683 cochlear hair cell ribbon synapse
GO:0099059 integral component of presynaptic active zone membrane
GO:0099635 voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels
GO:1901016 regulation of potassium ion transmembrane transporter activity
GO:1901379 regulation of potassium ion transmembrane transport
GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
GO:1990454 L-type voltage-gated calcium channel complex

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR002077 Voltage-dependent calcium channel, alpha-1 subunitFamilyFamily
IPR005446 Voltage-dependent calcium channel, L-type, alpha-1 subunitFamilyFamily
IPR005452 Voltage-dependent calcium channel, L-type, alpha-1D subunitFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR014873 Voltage-dependent calcium channel, alpha-1 subunit, IQ domainDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR031649 Voltage-dependent L-type calcium channel, IQ-associated domainDomainDomain
IPR031688 Voltage-gated calcium channel subunit alpha, C-terminalDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CAC1D_MOUSESTX1A_MOUSEBioGRID10468580 details
CAC1D_MOUSEAT1A1_MOUSEBioGRID10468580 details