Entity Details

Primary name Atrx
Entity type gene
Source Source Link

Details

PrimaryID22589
RefseqGene
SymbolAtrx
NameATRX, chromatin remodeler
ChromosomeX
LocationX 47.26 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-25
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsATRX_MOUSE

GO terms

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GOName
GO:0000212 meiotic spindle organization
GO:0000228 nuclear chromosome
GO:0000779 condensed chromosome, centromeric region
GO:0000781 chromosome, telomeric region
GO:0000792 heterochromatin
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005721 pericentric heterochromatin
GO:0005737 cytoplasm
GO:0006281 DNA repair
GO:0006334 nucleosome assembly
GO:0006336 DNA replication-independent nucleosome assembly
GO:0006338 chromatin remodeling
GO:0007283 spermatogenesis
GO:0010571 positive regulation of nuclear cell cycle DNA replication
GO:0015616 DNA translocase activity
GO:0016604 nuclear body
GO:0016605 PML body
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0030900 forebrain development
GO:0031297 replication fork processing
GO:0032206 positive regulation of telomere maintenance
GO:0035064 methylated histone binding
GO:0035128 post-embryonic forelimb morphogenesis
GO:0035264 multicellular organism growth
GO:0042393 histone binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0060009 Sertoli cell development
GO:0070087 chromo shadow domain binding
GO:0070192 chromosome organization involved in meiotic cell cycle
GO:0070198 protein localization to chromosome, telomeric region
GO:0070615 nucleosome-dependent ATPase activity
GO:0072520 seminiferous tubule development
GO:0072711 cellular response to hydroxyurea
GO:0099115 chromosome, subtelomeric region
GO:1900112 regulation of histone H3-K9 trimethylation
GO:1901581 negative regulation of telomeric RNA transcription from RNA pol II promoter
GO:1901582 positive regulation of telomeric RNA transcription from RNA pol II promoter
GO:1904908 negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

Diseases

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Interactions

36 interactions

InteractorPartnerSourcesPublicationsLink
AtrxMecp2BioGRID, DIP, MINT, UniProt17296936 20159591 24270455 details
AtrxEzh2BioGRID25417162 details
AtrxMECP2IntAct23452848 details
AtrxSmc1aBioGRID, UniProt20159591 details
AtrxDaxxBioGRID, DIP25938714 28358373 details
AtrxCtcfBioGRID20159591 details
AtrxArBioGRID21427128 details
AtrxH3f3aIntAct20211137 details
AtrxH3f3bIntAct20211137 details
AtrxMre11aUniProt24651726 details
AtrxPcnaUniProt24651726 details
AtrxSmc3BioGRID, UniProt20159591 details
AtrxJADE3BioGRID, IntAct26496610 details
AtrxPARP1BioGRID, IntAct26496610 details
AtrxBRWD1BioGRID, IntAct26496610 details
AtrxCBX4BioGRID, IntAct26496610 details
AtrxPHIPBioGRID, IntAct26496610 details
AtrxIVNS1ABPBioGRID, IntAct26496610 details
AtrxDAXXBioGRID, IntAct26496610 details
AtrxWDR76BioGRID, IntAct26496610 details
AtrxRBX1BioGRID, IntAct26496610 details
AtrxTOP2BBioGRID, IntAct26496610 details
AtrxORC1BioGRID, IntAct26496610 details
AtrxPWP2BioGRID, IntAct26496610 details
AtrxH2BC21BioGRID, IntAct26496610 details
AtrxCHD1BioGRID, IntAct26496610 details
AtrxKAT7BioGRID, IntAct26496610 details
AtrxDPY30BioGRID, IntAct26496610 details
AtrxUBTFBioGRID, IntAct26496610 details
AtrxSUPT16HBioGRID, IntAct26496610 details
AtrxTOP2ABioGRID, IntAct26496610 details
AtrxXpo7IntAct29748336 unassigned1673 details
AtrxHdac4BioGRID, MINT31040226 details
AtrxELOCBioGRID26496610 details
AtrxING5BioGRID26496610 details
AtrxCdx2BioGRID26206133 details