Entity Details

Primary name Yap1
Entity type gene
Source Source Link

Details

PrimaryID22601
RefseqGene
SymbolYap1
Nameyes-associated protein 1
Chromosome9
Location9
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsYAP1_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000902 cell morphogenesis
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001570 vasculogenesis
GO:0001674 female germ cell nucleus
GO:0001824 blastocyst development
GO:0001829 trophectodermal cell differentiation
GO:0001894 tissue homeostasis
GO:0003015 heart process
GO:0003143 embryonic heart tube morphogenesis
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006974 cellular response to DNA damage stimulus
GO:0006975 DNA damage induced protein phosphorylation
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0008283 cell population proliferation
GO:0008284 positive regulation of cell population proliferation
GO:0010468 regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010837 regulation of keratinocyte proliferation
GO:0016020 membrane
GO:0030216 keratinocyte differentiation
GO:0030857 negative regulation of epithelial cell differentiation
GO:0030903 notochord development
GO:0032570 response to progesterone
GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway
GO:0035019 somatic stem cell population maintenance
GO:0035329 hippo signaling
GO:0042060 wound healing
GO:0042127 regulation of cell population proliferation
GO:0045599 negative regulation of fat cell differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045747 positive regulation of Notch signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046622 positive regulation of organ growth
GO:0048339 paraxial mesoderm development
GO:0048368 lateral mesoderm development
GO:0050679 positive regulation of epithelial cell proliferation
GO:0050767 regulation of neurogenesis
GO:0050847 progesterone receptor signaling pathway
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060242 contact inhibition
GO:0060449 bud elongation involved in lung branching
GO:0060487 lung epithelial cell differentiation
GO:0060576 intestinal epithelial cell development
GO:0060828 regulation of canonical Wnt signaling pathway
GO:0061026 cardiac muscle tissue regeneration
GO:0065003 protein-containing complex assembly
GO:0070064 proline-rich region binding
GO:0070102 interleukin-6-mediated signaling pathway
GO:0071300 cellular response to retinoic acid
GO:0071480 cellular response to gamma radiation
GO:0072091 regulation of stem cell proliferation
GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0140297 DNA-binding transcription factor binding
GO:0140552 TEAD-YAP complex
GO:1900182 positive regulation of protein localization to nucleus
GO:1902018 negative regulation of cilium assembly
GO:1902459 positive regulation of stem cell population maintenance
GO:1904036 negative regulation of epithelial cell apoptotic process
GO:2000737 negative regulation of stem cell differentiation
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway

Diseases

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Interactions

103 interactions

InteractorPartnerSourcesPublicationsLink
Yap1TEAD1BioGRID, IntAct26496610 30865227 details
Yap1TEAD3BioGRID, IntAct26496610 30865227 details
Yap1RASSF8BioGRID, IntAct26496610 30865227 details
Yap1PALS1BioGRID, IntAct21145499 26496610 30865227 details
Yap1MPDZBioGRID, IntAct21145499 26496610 30865227 details
Yap1Pitx2DIP27251288 details
Yap1YAP1BioGRID, DIP28581498 30865227 details
Yap1Tead2BioGRID11358867 details
Yap1Tead3BioGRID11358867 details
Yap1Tead4BioGRID11358867 details
Yap1NFE2BioGRID9305852 details
Yap1TEAD4BioGRID26496610 30865227 details
Yap1PTPN14BioGRID30865227 details
Yap1CITBioGRID30865227 details
Yap1USP9XBioGRID30865227 details
Yap1FASNBioGRID30865227 details
Yap1MYH9BioGRID30865227 details
Yap1WWC3BioGRID30865227 details
Yap1TJP1BioGRID30865227 details
Yap1PRKDCBioGRID30865227 details
Yap1ALBBioGRID30865227 details
Yap1TUBBBioGRID30865227 details
Yap1TUBB4BBioGRID30865227 details
Yap1TUBB2ABioGRID30865227 details
Yap1TUBB4ABioGRID30865227 details
Yap1TUBA1BBioGRID30865227 details
Yap1TUBA1CBioGRID30865227 details
Yap1TUBB3BioGRID30865227 details
Yap1TUBB8BioGRID30865227 details
Yap1TUBB6BioGRID30865227 details
Yap1FBXW11BioGRID30865227 details
Yap1PDLIM7BioGRID30865227 details
Yap1SMAD3BioGRID30865227 details
Yap1CCDC85CBioGRID30865227 details
Yap1PPP2R2ABioGRID30865227 details
Yap1ATP5F1ABioGRID30865227 details
Yap1TRIP6BioGRID30865227 details
Yap1WBP2BioGRID30865227 details
Yap1ANXA11BioGRID30865227 details
Yap1HNRNPH1BioGRID30865227 details
Yap1GSRBioGRID30865227 details
Yap1LATS2BioGRID30865227 details
Yap1TP73MINT11278685 details
Yap1Trp73MINT11278685 details
Yap1Wwtr1BioGRID, IntAct16332960 21145499 details
Yap1Ddx17IntAct24581491 details
Yap1YWHAHBioGRID, IntAct21145499 26496610 details
Yap1AMOTL1BioGRID, IntAct21145499 26496610 details
Yap1LIN7CBioGRID, IntAct21145499 26496610 details
Yap1AMOTL2BioGRID, IntAct21145499 26496610 details
Yap1YWHAGBioGRID, IntAct21145499 26496610 details
Yap1YWHAZBioGRID, IntAct21145499 26496610 details
Yap1YWHABBioGRID, IntAct21145499 26496610 details
Yap1Klf4DIP25531778 details
Yap1POLR2ABioGRID9305852 details
Yap1Smad2BioGRID21145499 details
Yap1AMOTBioGRID21145499 details
Yap1LATS1BioGRID21145499 31578200 details
Yap1YWHAQBioGRID21145499 details
Yap1MPP7BioGRID21145499 details
Yap1YWHAEBioGRID21145499 details
Yap1Smad3BioGRID21145499 details
Yap1Pals1BioGRID21145499 details
Yap1Lin7cBioGRID21145499 32325033 details
Yap1PatjBioGRID21145499 details
Yap1AmotBioGRID21145499 details
Yap1MAPKAPK5BioGRID31578200 details
Yap1BTRCBioGRID31578200 details
Yap1CitBioGRID30865227 details
Yap1Lats2DIP, MINT18369314 28581498 details
Yap1Axin1IntAct24976009 details
Yap1TP53BP2BioGRID, IntAct26496610 details
Yap1GEMIN2BioGRID, IntAct26496610 details
Yap1PPP1CABioGRID, IntAct26496610 details
Yap1MECRBioGRID, IntAct26496610 details
Yap1NF2BioGRID, IntAct26496610 details
Yap1PARD3BioGRID, IntAct26496610 details
Yap1Dag1DIP28581498 details
Yap1SgcdDIP28581498 details
Yap1Ctnna1DIP28581498 details
Yap1Ctnnb1BioGRID32325033 details
Yap1Ppp1caBioGRID32325033 details
Yap1TsnaxBioGRID32325033 details
Yap1ArntBioGRID32325033 details
Yap1Arnt2BioGRID32325033 details
Yap1Bcl9lBioGRID32325033 details
Yap1Dach1BioGRID32325033 details
Yap1Dgcr8BioGRID32325033 details
Yap1DroshaBioGRID32325033 details
Yap1Gtpbp8BioGRID32325033 details
Yap1Rbl1BioGRID32325033 details
Yap1Rcor2BioGRID32325033 details
Yap1Slc9a3r2BioGRID32325033 details
Yap1Smad5BioGRID32325033 details
Yap1Tbx2BioGRID32325033 details
Yap1TfebBioGRID32325033 details
Yap1Wbp2BioGRID32325033 details
Yap1Atpif1BioGRID32325033 details
Yap1Ccdc85cBioGRID32325033 details
Yap1Rb1BioGRID32325033 details
Yap1RbpjlBioGRID32325033 details
Yap1Zeb1BioGRID32325033 details
Yap1Id2IntAct19914168 details