Entity Details

Primary name DERL1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ99J56
EntryNameDERL1_MOUSE
FullNameDerlin-1
TaxID10090
Evidenceevidence at protein level
Length251
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesDerl1

GO terms

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GOName
GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex
GO:0002020 protease binding
GO:0005047 signal recognition particle binding
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005783 endoplasmic reticulum
GO:0006986 response to unfolded protein
GO:0016021 integral component of membrane
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0030970 retrograde protein transport, ER to cytosol
GO:0031398 positive regulation of protein ubiquitination
GO:0031625 ubiquitin protein ligase binding
GO:0031648 protein destabilization
GO:0032092 positive regulation of protein binding
GO:0034620 cellular response to unfolded protein
GO:0036502 Derlin-1-VIMP complex
GO:0036503 ERAD pathway
GO:0036513 Derlin-1 retrotranslocation complex
GO:0042288 MHC class I protein binding
GO:0042802 identical protein binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044322 endoplasmic reticulum quality control compartment
GO:0044877 protein-containing complex binding
GO:0051117 ATPase binding
GO:0051787 misfolded protein binding
GO:0071712 ER-associated misfolded protein catabolic process
GO:1990381 ubiquitin-specific protease binding

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR007599 DerlinFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DERL1_MOUSEUBC_MOUSEBioGRID28190767 details
DERL1_MOUSESCNNA_MOUSEBioGRID28137758 details