Entity Details

Primary name CDK9_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ99J95
EntryNameCDK9_MOUSE
FullNameCyclin-dependent kinase 9
TaxID10090
Evidenceevidence at protein level
Length372
SequenceStatuscomplete
DateCreated2005-02-01
DateModified2021-06-02

Ontological Relatives

GenesCdk9

GO terms

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GOName
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001223 transcription coactivator binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006281 DNA repair
GO:0006282 regulation of DNA repair
GO:0006468 protein phosphorylation
GO:0008023 transcription elongation factor complex
GO:0008024 cyclin/CDK positive transcription elongation factor complex
GO:0008134 transcription factor binding
GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0016592 mediator complex
GO:0016605 PML body
GO:0017069 snRNA binding
GO:0019901 protein kinase binding
GO:0031056 regulation of histone modification
GO:0031297 replication fork processing
GO:0033129 positive regulation of histone phosphorylation
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0042493 response to drug
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051147 regulation of muscle cell differentiation
GO:0070691 P-TEFb complex
GO:0070816 phosphorylation of RNA polymerase II C-terminal domain
GO:0071345 cellular response to cytokine stimulus
GO:0097322 7SK snRNA binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1900364 negative regulation of mRNA polyadenylation
GO:1903839 positive regulation of mRNA 3'-UTR binding
GO:2001168 positive regulation of histone H2B ubiquitination

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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