Entity Details

Primary name TNIP2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ99JG7
EntryNameTNIP2_MOUSE
FullNameTNFAIP3-interacting protein 2
TaxID10090
Evidenceevidence at protein level
Length430
SequenceStatuscomplete
DateCreated2008-02-26
DateModified2021-06-02

Ontological Relatives

GenesTnip2

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0019901 protein kinase binding
GO:0023035 CD40 signaling pathway
GO:0031593 polyubiquitin modification-dependent protein binding
GO:0034134 toll-like receptor 2 signaling pathway
GO:0034138 toll-like receptor 3 signaling pathway
GO:0034162 toll-like receptor 9 signaling pathway
GO:0043032 positive regulation of macrophage activation
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0050821 protein stabilization
GO:0050871 positive regulation of B cell activation
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding
GO:0071222 cellular response to lipopolysaccharide
GO:2000352 negative regulation of endothelial cell apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR022008 TSG101 and ALIX binding domain of CEP55DomainDomain
IPR032419 NF-kappa-B essential modulator NEMO, CC2-LZ domainDomainDomain
IPR034735 NEMO, Zinc fingerDomainDomain

Diseases

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Interactions

0 interactions

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