Entity Details

Primary name Nppa
Entity type gene
Source Source Link

Details

PrimaryID230899
RefseqGene
SymbolNppa
Namenatriuretic peptide type A
Chromosome4
Location4 78.66 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-05-05
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsANF_MOUSE

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0003085 negative regulation of systemic arterial blood pressure
GO:0005102 signaling receptor binding
GO:0005179 hormone activity
GO:0005184 neuropeptide hormone activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005903 brush border
GO:0006182 cGMP biosynthetic process
GO:0006457 protein folding
GO:0007168 receptor guanylyl cyclase signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007565 female pregnancy
GO:0008217 regulation of blood pressure
GO:0010460 positive regulation of heart rate
GO:0010753 positive regulation of cGMP-mediated signaling
GO:0014898 cardiac muscle hypertrophy in response to stress
GO:0019934 cGMP-mediated signaling
GO:0030308 negative regulation of cell growth
GO:0032868 response to insulin
GO:0032991 protein-containing complex
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042311 vasodilation
GO:0042629 mast cell granule
GO:0042995 cell projection
GO:0043204 perikaryon
GO:0043508 negative regulation of JUN kinase activity
GO:0048471 perinuclear region of cytoplasm
GO:0051427 hormone receptor binding
GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization
GO:0060452 positive regulation of cardiac muscle contraction
GO:0061049 cell growth involved in cardiac muscle cell development
GO:0071260 cellular response to mechanical stimulus
GO:0071855 neuropeptide receptor binding
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1901841 regulation of high voltage-gated calcium channel activity
GO:1902261 positive regulation of delayed rectifier potassium channel activity
GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
GO:1903595 positive regulation of histamine secretion by mast cell
GO:1903766 positive regulation of potassium ion export across plasma membrane
GO:1903815 negative regulation of collecting lymphatic vessel constriction

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
NppaCaprin1IntAct15102471 details
NppaG6pdxIntAct15102471 details
NppaPkmIntAct15102471 details