Entity Details

Primary name Lrrk1
Entity type gene
Source Source Link

Details

PrimaryID233328
RefseqGene
SymbolLrrk1
Nameleucine-rich repeat kinase 1
Chromosome7
Location7
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-05-05
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsLRRK1_MOUSE

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0036035 osteoclast development
GO:0042802 identical protein binding
GO:0045453 bone resorption
GO:0046872 metal ion binding
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1902533 positive regulation of intracellular signal transduction

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
Lrrk1Grb2BioGRID, IntAct20697350 details
Lrrk1Shc1BioGRID, IntAct20697350 details
Lrrk1Dapk1BioGRID32325033 details
Lrrk1Gpbp1l1BioGRID32325033 details
Lrrk1Nek1BioGRID32325033 details
Lrrk1Vgll4BioGRID32325033 details