Entity Details

Primary name Plcg2
Entity type gene
Source Source Link

Details

PrimaryID234779
RefseqGene
SymbolPlcg2
Namephospholipase C, gamma 2
Chromosome8
Location8 64.26 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-05-05
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPLCG2_MOUSE

GO terms

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GOName
GO:0001784 phosphotyrosine residue binding
GO:0002092 positive regulation of receptor internalization
GO:0002316 follicular B cell differentiation
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0004629 phospholipase C activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006661 phosphatidylinositol biosynthetic process
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0009395 phospholipid catabolic process
GO:0010468 regulation of gene expression
GO:0010634 positive regulation of epithelial cell migration
GO:0016020 membrane
GO:0019722 calcium-mediated signaling
GO:0019901 protein kinase binding
GO:0030183 B cell differentiation
GO:0032026 response to magnesium ion
GO:0032237 activation of store-operated calcium channel activity
GO:0032481 positive regulation of type I interferon production
GO:0032496 response to lipopolysaccharide
GO:0032959 inositol trisphosphate biosynthetic process
GO:0033198 response to ATP
GO:0043069 negative regulation of programmed cell death
GO:0050852 T cell receptor signaling pathway
GO:0050853 B cell receptor signaling pathway
GO:0051209 release of sequestered calcium ion into cytosol
GO:0071277 cellular response to calcium ion
GO:0097110 scaffold protein binding
GO:0140031 phosphorylation-dependent protein binding

Diseases

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Interactions

44 interactions

InteractorPartnerSourcesPublicationsLink
Plcg2GsnIntAct15102471 details
Plcg2Ndc80IntAct15102471 details
Plcg2Pdcd6ipIntAct15102471 details
Plcg2Cap1IntAct15102471 details
Plcg2Dvl2IntAct15102471 details
Plcg2Fn1IntAct15102471 details
Plcg2FlnaIntAct15102471 details
Plcg2Trim27IntAct15102471 details
Plcg2Spry2IntAct15102471 details
Plcg2Uck1IntAct15102471 details
Plcg2Sptbn1IntAct15102471 details
Plcg2Bach2IntAct15102471 details
Plcg2Phc2IntAct15102471 details
Plcg2Tox4IntAct15102471 details
Plcg2Hax1IntAct15102471 details
Plcg2Nbr1IntAct15102471 details
Plcg2Reps1IntAct15102471 details
Plcg2Sh3kbp1IntAct15102471 details
Plcg2Inpp5dIntAct15102471 details
Plcg2Dynlt1fIntAct15102471 details
Plcg2Dynlt1cIntAct15102471 details
Plcg2Dynlt1aIntAct15102471 details
Plcg2Dynlt1bIntAct15102471 details
Plcg2Zbtb7bIntAct15102471 details
Plcg2Epb41l2IntAct15102471 details
Plcg2Sos2IntAct15102471 details
Plcg2Errfi1IntAct15102471 details
Plcg2Fhl2IntAct15102471 details
Plcg2CryabIntAct15102471 details
Plcg2CSF1RMINT9312046 details
Plcg2Csf1rBioGRID9312046 details
Plcg2Itgb2BioGRID30333137 details
Plcg2EporIntAct15953601 details
Plcg2LynMINT8395016 details
Plcg2BlkMINT8395016 details
Plcg2FynMINT8395016 details
Plcg2Fancd2BioGRID28378742 details
Plcg2Atg16l1BioGRID30196744 details
Plcg2Arpc1bBioGRID32325033 details
Plcg2NplBioGRID32325033 details
Plcg2Grb2BioGRID32325033 details
Plcg2Map2k4BioGRID32325033 details
Plcg2Sec23bBioGRID32325033 details
Plcg2Gab1BioGRID32325033 details