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Entity Details
Primary name
Topbp1
Entity type
gene
Source
Source Link
Details
PrimaryID
235559
RefseqGene
Symbol
Topbp1
Name
topoisomerase (DNA) II binding protein 1
Chromosome
9
Location
9
TaxID
10090
Status
live
SourceGenome
genomic
SourceOrigin
natural
CreationDate
2002-05-05
ModificationDate
2021-06-23
Ontological Relatives
UniProt IDs
TOPB1_MOUSE
GO terms
Show/Hide Table
GO
Name
GO:0000794
condensed nuclear chromosome
GO:0000922
spindle pole
GO:0001673
male germ cell nucleus
GO:0003677
DNA binding
GO:0005654
nucleoplasm
GO:0005694
chromosome
GO:0005737
cytoplasm
GO:0005815
microtubule organizing center
GO:0005886
plasma membrane
GO:0006270
DNA replication initiation
GO:0006281
DNA repair
GO:0006974
cellular response to DNA damage stimulus
GO:0007095
mitotic G2 DNA damage checkpoint signaling
GO:0007131
reciprocal meiotic recombination
GO:0010212
response to ionizing radiation
GO:0015629
actin cytoskeleton
GO:0016604
nuclear body
GO:0016605
PML body
GO:0033314
mitotic DNA replication checkpoint signaling
GO:0042802
identical protein binding
GO:0043231
intracellular membrane-bounded organelle
Diseases
Show/Hide Table
Interactions
17 interactions
Interactor
Partner
Sources
Publications
Link
Topbp1
Atrip
MINT
20871591
details
Topbp1
H2ax
MINT
20871591
details
Topbp1
E2f1
BioGRID
17006541
details
Topbp1
BMPR2
IntAct
15188402
details
Topbp1
Trpm7
IntAct
24855944
details
Topbp1
ERI1
BioGRID, IntAct
26496610
details
Topbp1
MRPL3
BioGRID, IntAct
26496610
details
Topbp1
PRICKLE3
BioGRID, IntAct
26496610
details
Topbp1
RBM25
BioGRID, IntAct
26496610
details
Topbp1
Foxp3
BioGRID
22922362
details
Topbp1
POP7
BioGRID
26496610
details
Topbp1
TTC31
BioGRID
26496610
details
Topbp1
STUB1
BioGRID
29091030
details
Topbp1
Nbn
BioGRID
32325033
details
Topbp1
Rbbp8
BioGRID
32325033
details
Topbp1
Blm
BioGRID
32325033
details
Topbp1
Msh6
BioGRID
32325033
details
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