Entity Details

Primary name ACON_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ99KI0
EntryNameACON_MOUSE
FullNameAconitate hydratase, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length780
SequenceStatuscomplete
DateCreated2005-02-01
DateModified2021-06-02

Ontological Relatives

GenesAco2

GO terms

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GOName
GO:0001889 liver development
GO:0003994 aconitate hydratase activity
GO:0005506 iron ion binding
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006099 tricarboxylic acid cycle
GO:0006101 citrate metabolic process
GO:0006102 isocitrate metabolic process
GO:0035900 response to isolation stress
GO:0043209 myelin sheath
GO:0047780 citrate dehydratase activity
GO:0051538 3 iron, 4 sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domainDomainDomain
IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domainDomainDomain
IPR006248 Aconitase, mitochondrial-likeFamilyFamily
IPR015928 Aconitase/3-isopropylmalate dehydratase, swivelFamilyHomologous superfamily
IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3FamilyHomologous superfamily
IPR015932 Aconitase, domain 2FamilyHomologous superfamily
IPR018136 Aconitase family, 4Fe-4S cluster binding siteSiteBinding site
IPR036008 Aconitase, iron-sulfur domainFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ACON_MOUSEITPR1_MOUSEIntAct15652484 details
ACON_MOUSENEB2_MOUSEBioGRID28634551 30562941 details