Entity Details

Primary name NAMPT_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ99KQ4
EntryNameNAMPT_MOUSE
FullNameNicotinamide phosphoribosyltransferase
TaxID10090
Evidenceevidence at protein level
Length491
SequenceStatuscomplete
DateCreated2005-07-05
DateModified2021-06-02

Ontological Relatives

GenesNampt

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0001774 microglial cell activation
GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007565 female pregnancy
GO:0007568 aging
GO:0007623 circadian rhythm
GO:0009435 NAD biosynthetic process
GO:0010507 negative regulation of autophagy
GO:0014070 response to organic cyclic compound
GO:0014916 regulation of lung blood pressure
GO:0016607 nuclear speck
GO:0030054 cell junction
GO:0032922 circadian regulation of gene expression
GO:0042802 identical protein binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0047280 nicotinamide phosphoribosyltransferase activity
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
GO:0070997 neuron death
GO:0071479 cellular response to ionizing radiation
GO:0090650 cellular response to oxygen-glucose deprivation
GO:1904646 cellular response to amyloid-beta
GO:1905377 response to D-galactose
GO:2000773 negative regulation of cellular senescence

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR016471 Nicotinamide phosphoribosyl transferaseFamilyFamily
IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminalFamilyHomologous superfamily
IPR041525 Nicotinate/nicotinamide phosphoribosyltransferaseDomainDomain
IPR041529 Nicotinamide phosphoribosyltransferase, N-terminal domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
NAMPT_MOUSENAMPT_MOUSEDIP16783373 16783377 details