Entity Details

Primary name Pde5a
Entity type gene
Source Source Link

Details

PrimaryID242202
RefseqGene
SymbolPde5a
Namephosphodiesterase 5A, cGMP-specific
Chromosome3
Location3
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-05-06
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPDE5A_MOUSE

GO terms

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GOName
GO:0002026 regulation of the force of heart contraction
GO:0002678 positive regulation of chronic inflammatory response
GO:0004112 cyclic-nucleotide phosphodiesterase activity
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0007614 short-term memory
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0010749 regulation of nitric oxide mediated signal transduction
GO:0030553 cGMP binding
GO:0042130 negative regulation of T cell proliferation
GO:0043065 positive regulation of apoptotic process
GO:0043406 positive regulation of MAP kinase activity
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway
GO:0045907 positive regulation of vasoconstriction
GO:0046068 cGMP metabolic process
GO:0046069 cGMP catabolic process
GO:0046872 metal ion binding
GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity
GO:0055118 negative regulation of cardiac muscle contraction
GO:0055119 relaxation of cardiac muscle
GO:0060282 positive regulation of oocyte development

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
Pde5aPpp1cabhf-ucl, BioGRID25593058 29669786 details
Pde5aPde3aBioGRID32325033 details
Pde5aPde10aBioGRID32325033 details
Pde5aPde7aBioGRID32325033 details
Pde5aPde6cBioGRID32325033 details