Entity Details

Primary name PARK7_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ99LX0
EntryNamePARK7_MOUSE
FullNameParkinson disease protein 7 homolog
TaxID10090
Evidenceevidence at protein level
Length189
SequenceStatuscomplete
DateCreated2004-12-07
DateModified2021-06-02

Ontological Relatives

GenesPark7

GO terms

Show/Hide Table
GOName
GO:0000785 chromatin
GO:0001933 negative regulation of protein phosphorylation
GO:0001963 synaptic transmission, dopaminergic
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus
GO:0003713 transcription coactivator activity
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005102 signaling receptor binding
GO:0005507 copper ion binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005759 mitochondrial matrix
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006281 DNA repair
GO:0006469 negative regulation of protein kinase activity
GO:0006517 protein deglycosylation
GO:0006914 autophagy
GO:0006954 inflammatory response
GO:0006979 response to oxidative stress
GO:0007005 mitochondrion organization
GO:0007338 single fertilization
GO:0008134 transcription factor binding
GO:0008233 peptidase activity
GO:0008344 adult locomotory behavior
GO:0010273 detoxification of copper ion
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016532 superoxide dismutase copper chaperone activity
GO:0016570 histone modification
GO:0016605 PML body
GO:0016684 oxidoreductase activity, acting on peroxide as acceptor
GO:0019249 lactate biosynthetic process
GO:0019826 oxygen sensor activity
GO:0019899 enzyme binding
GO:0019900 kinase binding
GO:0019955 cytokine binding
GO:0030073 insulin secretion
GO:0030424 axon
GO:0031334 positive regulation of protein-containing complex assembly
GO:0031397 negative regulation of protein ubiquitination
GO:0032091 negative regulation of protein binding
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032757 positive regulation of interleukin-8 production
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0033182 regulation of histone ubiquitination
GO:0033234 negative regulation of protein sumoylation
GO:0033864 positive regulation of NAD(P)H oxidase activity
GO:0034599 cellular response to oxidative stress
GO:0034614 cellular response to reactive oxygen species
GO:0035065 regulation of histone acetylation
GO:0036470 tyrosine 3-monooxygenase activator activity
GO:0036471 cellular response to glyoxal
GO:0036478 L-dopa decarboxylase activator activity
GO:0036524 protein deglycase activity
GO:0036526 peptidyl-cysteine deglycation
GO:0036527 peptidyl-arginine deglycation
GO:0036528 peptidyl-lysine deglycation
GO:0036529 protein deglycation, glyoxal removal
GO:0036530 protein deglycation, methylglyoxal removal
GO:0036531 glutathione deglycation
GO:0042177 negative regulation of protein catabolic process
GO:0042542 response to hydrogen peroxide
GO:0042593 glucose homeostasis
GO:0042743 hydrogen peroxide metabolic process
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043005 neuron projection
GO:0043066 negative regulation of apoptotic process
GO:0043523 regulation of neuron apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0044297 cell body
GO:0044388 small protein activating enzyme binding
GO:0044390 ubiquitin-like protein conjugating enzyme binding
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0045340 mercury ion binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046295 glycolate biosynthetic process
GO:0046826 negative regulation of protein export from nucleus
GO:0048471 perinuclear region of cytoplasm
GO:0050681 androgen receptor binding
GO:0050727 regulation of inflammatory response
GO:0050787 detoxification of mercury ion
GO:0050821 protein stabilization
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051444 negative regulation of ubiquitin-protein transferase activity
GO:0051583 dopamine uptake involved in synaptic transmission
GO:0051881 regulation of mitochondrial membrane potential
GO:0051899 membrane depolarization
GO:0051920 peroxiredoxin activity
GO:0060081 membrane hyperpolarization
GO:0060548 negative regulation of cell death
GO:0060765 regulation of androgen receptor signaling pathway
GO:0061727 methylglyoxal catabolic process to lactate
GO:0061827 sperm head
GO:0070301 cellular response to hydrogen peroxide
GO:0070994 detection of oxidative stress
GO:0097110 scaffold protein binding
GO:0098793 presynapse
GO:0106044 guanine deglycation
GO:0106045 guanine deglycation, methylglyoxal removal
GO:0106046 guanine deglycation, glyoxal removal
GO:0110095 cellular detoxification of aldehyde
GO:0140041 cellular detoxification of methylglyoxal
GO:1900182 positive regulation of protein localization to nucleus
GO:1901215 negative regulation of neuron death
GO:1901671 positive regulation of superoxide dismutase activity
GO:1901984 negative regulation of protein acetylation
GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1902958 positive regulation of mitochondrial electron transport, NADH to ubiquinone
GO:1903094 negative regulation of protein K48-linked deubiquitination
GO:1903122 negative regulation of TRAIL-activated apoptotic signaling pathway
GO:1903135 cupric ion binding
GO:1903136 cuprous ion binding
GO:1903168 positive regulation of pyrroline-5-carboxylate reductase activity
GO:1903178 positive regulation of tyrosine 3-monooxygenase activity
GO:1903181 positive regulation of dopamine biosynthetic process
GO:1903189 glyoxal metabolic process
GO:1903197 positive regulation of L-dopa biosynthetic process
GO:1903200 positive regulation of L-dopa decarboxylase activity
GO:1903202 negative regulation of oxidative stress-induced cell death
GO:1903204 negative regulation of oxidative stress-induced neuron death
GO:1903206 negative regulation of hydrogen peroxide-induced cell death
GO:1903208 negative regulation of hydrogen peroxide-induced neuron death
GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
GO:1903384 negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
GO:1903427 negative regulation of reactive oxygen species biosynthetic process
GO:1903428 positive regulation of reactive oxygen species biosynthetic process
GO:1904782 negative regulation of NMDA glutamate receptor activity
GO:1905259 negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
GO:1905516 positive regulation of fertilization
GO:1990381 ubiquitin-specific protease binding
GO:1990422 glyoxalase (glycolic acid-forming) activity
GO:2000157 negative regulation of ubiquitin-specific protease activity
GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity
GO:2000679 positive regulation of transcription regulatory region DNA binding
GO:2000825 positive regulation of androgen receptor activity
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway
GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cytoplasm
Endoplasmic reticulum
Membrane raft
Mitochondrion
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR002818 DJ-1/PfpIDomainDomain
IPR006287 Protein/nucleic acid deglycase DJ-1FamilyFamily
IPR029062 Class I glutamine amidotransferase-likeFamilyHomologous superfamily

Diseases

Show/Hide Table