Entity Details

Primary name Klrk1
Entity type gene
Source Source Link

Details

PrimaryID27007
RefseqGene
SymbolKlrk1
Namekiller cell lectin-like receptor subfamily K, member 1
Chromosome6
Location6 63.44 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-12-21
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsNKG2D_MOUSE

GO terms

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GOName
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002250 adaptive immune response
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0019900 kinase binding
GO:0030101 natural killer cell activation
GO:0030154 cell differentiation
GO:0030246 carbohydrate binding
GO:0030887 positive regulation of myeloid dendritic cell activation
GO:0032394 MHC class Ib receptor activity
GO:0032729 positive regulation of interferon-gamma production
GO:0038023 signaling receptor activity
GO:0042288 MHC class I protein binding
GO:0043065 positive regulation of apoptotic process
GO:0045087 innate immune response
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0050830 defense response to Gram-positive bacterium
GO:0071222 cellular response to lipopolysaccharide

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
Klrk1Raet1bIntAct11825567 details
Klrk1HcstBioGRID12426564 12426565 details
Klrk1TyrobpBioGRID12426564 12426565 details