Entity Details

Primary name Eif2ak4
Entity type gene
Source Source Link

Details

PrimaryID27103
RefseqGene
SymbolEif2ak4
Nameeukaryotic translation initiation factor 2 alpha kinase 4
Chromosome2
Location2
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-04-05
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsE2AK4_MOUSE

GO terms

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GOName
GO:0000049 tRNA binding
GO:0000077 DNA damage checkpoint signaling
GO:0001934 positive regulation of protein phosphorylation
GO:0002230 positive regulation of defense response to virus by host
GO:0002250 adaptive immune response
GO:0002286 T cell activation involved in immune response
GO:0002821 positive regulation of adaptive immune response
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005844 polysome
GO:0006446 regulation of translational initiation
GO:0006468 protein phosphorylation
GO:0007612 learning
GO:0007616 long-term memory
GO:0009267 cellular response to starvation
GO:0010628 positive regulation of gene expression
GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation
GO:0017148 negative regulation of translation
GO:0019081 viral translation
GO:0022626 cytosolic ribosome
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0032057 negative regulation of translational initiation in response to stress
GO:0032792 negative regulation of CREB transcription factor activity
GO:0034198 cellular response to amino acid starvation
GO:0034644 cellular response to UV
GO:0034976 response to endoplasmic reticulum stress
GO:0036492 eiF2alpha phosphorylation in response to endoplasmic reticulum stress
GO:0039520 induction by virus of host autophagy
GO:0043558 regulation of translational initiation in response to stress
GO:0044828 negative regulation by host of viral genome replication
GO:0045665 negative regulation of neuron differentiation
GO:0045947 negative regulation of translational initiation
GO:0046777 protein autophosphorylation
GO:0051607 defense response to virus
GO:0060259 regulation of feeding behavior
GO:0070417 cellular response to cold
GO:0071074 eukaryotic initiation factor eIF2 binding
GO:0071264 positive regulation of translational initiation in response to starvation
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0140469 GCN2-mediated signaling
GO:1900273 positive regulation of long-term synaptic potentiation
GO:1990138 neuron projection extension
GO:1990253 cellular response to leucine starvation

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
Eif2ak4SMAD4BioGRID15761153 details
Eif2ak4TGFBR1BioGRID15761153 details