Entity Details

Primary name Trp53bp1
Entity type gene
Source Source Link

Details

PrimaryID27223
RefseqGene
SymbolTrp53bp1
Nametransformation related protein 53 binding protein 1
Chromosome2
Location2
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-04-05
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsTP53B_MOUSE

GO terms

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GOName
GO:0000077 DNA damage checkpoint signaling
GO:0000776 kinetochore
GO:0000781 chromosome, telomeric region
GO:0002039 p53 binding
GO:0003684 damaged DNA binding
GO:0003712 transcription coregulator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005657 replication fork
GO:0005737 cytoplasm
GO:0006281 DNA repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006355 regulation of transcription, DNA-templated
GO:0006974 cellular response to DNA damage stimulus
GO:0008134 transcription factor binding
GO:0016604 nuclear body
GO:0035064 methylated histone binding
GO:0035861 site of double-strand break
GO:0042162 telomeric DNA binding
GO:0042393 histone binding
GO:0043565 sequence-specific DNA binding
GO:0045830 positive regulation of isotype switching
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051260 protein homooligomerization
GO:0061649 ubiquitin modification-dependent histone binding
GO:0071481 cellular response to X-ray
GO:1990391 DNA repair complex
GO:2000042 negative regulation of double-strand break repair via homologous recombination

Diseases

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Interactions

36 interactions

InteractorPartnerSourcesPublicationsLink
Trp53bp1Rnf168BioGRID24324146 details
Trp53bp1Itgb3BioGRID30333137 details
Trp53bp1Grin1BioGRID, IntAct10862698 16635246 details
Trp53bp1Smurf2BioGRID, IntAct19379695 details
Trp53bp1H2axBioGRID, MINT12792649 20871591 details
Trp53bp1Paxip1UniProt26744420 details
Trp53bp1PLK1DIP20126263 details
Trp53bp1Mdc1BioGRID18678890 24324146 details
Trp53bp1Arrb1BioGRID31506606 details
Trp53bp1Grin2bMINT10862698 details
Trp53bp1MRPL11BioGRID, IntAct26496610 details
Trp53bp1ARHGAP17BioGRID, IntAct26496610 details
Trp53bp1ZBTB11BioGRID, IntAct26496610 details
Trp53bp1PYCR3BioGRID, IntAct26496610 details
Trp53bp1CHAMP1BioGRID, IntAct26496610 details
Trp53bp1CENPFBioGRID, IntAct26496610 details
Trp53bp1AKR7A2BioGRID, IntAct26496610 details
Trp53bp1ZSWIM9BioGRID, IntAct26496610 details
Trp53bp1PSMD2BioGRID, IntAct26496610 details
Trp53bp1ERGIC1BioGRID, IntAct26496610 details
Trp53bp1USP28BioGRID, IntAct26496610 details
Trp53bp1ZNF281BioGRID, IntAct26496610 details
Trp53bp1Trp53DIP19556538 details
Trp53bp1Fxr1BioGRID, IntAct28671696 details
Trp53bp1Herc2BioGRID, IntAct28671696 details
Trp53bp1Huwe1BioGRID, IntAct28671696 details
Trp53bp1Pde4dipBioGRID, IntAct28671696 details
Trp53bp1TnikBioGRID, IntAct28671696 details
Trp53bp1Tsc1BioGRID, IntAct28671696 details
Trp53bp1CDC73MINT29774127 details
Trp53bp1Pou5f1BioGRID22083510 details
Trp53bp1TAF1BioGRID26496610 details
Trp53bp1TYK2BioGRID26496610 details
Trp53bp1WBP2BioGRID26496610 details
Trp53bp1NUDT16L1BioGRID26496610 details
Trp53bp1Chaf1aBioGRID26365490 details