Entity Details

Primary name DNJA3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ99M87
EntryNameDNJA3_MOUSE
FullNameDnaJ homolog subfamily A member 3, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length480
SequenceStatuscomplete
DateCreated2003-05-16
DateModified2021-06-02

Ontological Relatives

GenesDnaja3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0005133 interferon-gamma receptor binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0006264 mitochondrial DNA replication
GO:0006457 protein folding
GO:0006469 negative regulation of protein kinase activity
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006924 activation-induced cell death of T cells
GO:0007005 mitochondrion organization
GO:0007264 small GTPase mediated signal transduction
GO:0007528 neuromuscular junction development
GO:0007569 cell aging
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0009408 response to heat
GO:0019897 extrinsic component of plasma membrane
GO:0019901 protein kinase binding
GO:0030544 Hsp70 protein binding
GO:0030695 GTPase regulator activity
GO:0030971 receptor tyrosine kinase binding
GO:0031398 positive regulation of protein ubiquitination
GO:0031594 neuromuscular junction
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0033077 T cell differentiation in thymus
GO:0034341 response to interferon-gamma
GO:0042102 positive regulation of T cell proliferation
GO:0042645 mitochondrial nucleoid
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043069 negative regulation of programmed cell death
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0044877 protein-containing complex binding
GO:0045211 postsynaptic membrane
GO:0046872 metal ion binding
GO:0050821 protein stabilization
GO:0051059 NF-kappaB binding
GO:0051082 unfolded protein binding
GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway
GO:0071340 skeletal muscle acetylcholine-gated channel clustering
GO:0106137 IkappaB kinase complex binding

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR001305 Heat shock protein DnaJ, cysteine-rich domainDomainDomain
IPR001623 DnaJ domainDomainDomain
IPR002939 Chaperone DnaJ, C-terminalDomainDomain
IPR008971 HSP40/DnaJ peptide-bindingFamilyHomologous superfamily
IPR012724 Chaperone DnaJFamilyFamily
IPR018253 DnaJ domain, conserved siteSiteConserved site
IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR036869 Chaperone J-domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DNJA3_MOUSETRAF1_MOUSEIntAct15102471 details
DNJA3_MOUSEGRP75_MOUSEBioGRID16327803 details