Entity Details

Primary name Iqgap1
Entity type gene
Source Source Link

Details

PrimaryID29875
RefseqGene
SymbolIqgap1
NameIQ motif containing GTPase activating protein 1
Chromosome7
Location7 45.68 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-18
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsIQGA1_MOUSE

GO terms

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GOName
GO:0001726 ruffle
GO:0001817 regulation of cytokine production
GO:0005078 MAP-kinase scaffold activity
GO:0005096 GTPase activator activity
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005925 focal adhesion
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007346 regulation of mitotic cell cycle
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010761 fibroblast migration
GO:0016328 lateral plasma membrane
GO:0016477 cell migration
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0019904 protein domain specific binding
GO:0030424 axon
GO:0030426 growth cone
GO:0030496 midbody
GO:0030864 cortical actin cytoskeleton
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031252 cell leading edge
GO:0031267 small GTPase binding
GO:0032956 regulation of actin cytoskeleton organization
GO:0032991 protein-containing complex
GO:0035305 negative regulation of dephosphorylation
GO:0036057 slit diaphragm
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0043005 neuron projection
GO:0043406 positive regulation of MAP kinase activity
GO:0043410 positive regulation of MAPK cascade
GO:0043539 protein serine/threonine kinase activator activity
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0044548 S100 protein binding
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0045860 positive regulation of protein kinase activity
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0051894 positive regulation of focal adhesion assembly
GO:0060090 molecular adaptor activity
GO:0071277 cellular response to calcium ion
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0072015 glomerular visceral epithelial cell development
GO:1900006 positive regulation of dendrite development
GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation
GO:1903829 positive regulation of cellular protein localization
GO:1904754 positive regulation of vascular associated smooth muscle cell migration
GO:1990138 neuron projection extension
GO:1990776 response to angiotensin
GO:1990904 ribonucleoprotein complex

Diseases

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Interactions

82 interactions

InteractorPartnerSourcesPublicationsLink
Iqgap1Traf1IntAct15102471 details
Iqgap1Camk2aIntAct15102471 details
Iqgap1Shc1MINT20075861 details
Iqgap1Itgb1BioGRID30333137 details
Iqgap1Itgb3BioGRID30333137 details
Iqgap1Diaph1mbinfo17620407 details
Iqgap1WaslBioGRID, MINT23982733 32325033 details
Iqgap1Dmrt2BioGRID20975687 details
Iqgap1Cdc42BioGRID16369480 32325033 details
Iqgap1Pafah1b1BioGRID16369480 details
Iqgap1Clip1BioGRID16369480 32325033 details
Iqgap1Csf1IntAct16267818 details
Iqgap1Sting1InnateDB23263557 details
Iqgap1WRAP73UniProt26675238 details
Iqgap1CblBioGRID, IntAct27474268 32325033 details
Iqgap1Mycbp2BioGRID, IntAct28671696 details
Iqgap1Agap2BioGRID, IntAct28706196 details
Iqgap1Syngap1BioGRID, IntAct28706196 details
Iqgap1Hdac4BioGRID, MINT31040226 details
Iqgap1C9orf72BioGRID, MINT27103069 details
Iqgap1Foxp3BioGRID22922362 details
Iqgap1Klhl40BioGRID24960163 details
Iqgap1EedBioGRID24457600 details
Iqgap1Elf5BioGRID26584622 details
Iqgap1Fancd2BioGRID28378742 details
Iqgap1BrafBioGRID27034005 details
Iqgap1Wdfy4BioGRID30409884 details
Iqgap1Atxn1BioGRID30457570 details
Iqgap1Cct2BioGRID32325033 details
Iqgap1CkbBioGRID32325033 details
Iqgap1Eif4eBioGRID32325033 details
Iqgap1EzrBioGRID32325033 details
Iqgap1HdgfBioGRID32325033 details
Iqgap1Isg15BioGRID32325033 details
Iqgap1Lsm8BioGRID32325033 details
Iqgap1PlekBioGRID32325033 details
Iqgap1Rrbp1BioGRID32325033 details
Iqgap1Psma1BioGRID32325033 details
Iqgap1Eif2s3xBioGRID32325033 details
Iqgap1Ilf3BioGRID32325033 details
Iqgap1ActbBioGRID32325033 details
Iqgap1Actn4BioGRID32325033 details
Iqgap1Api5BioGRID32325033 details
Iqgap1Cap1BioGRID32325033 details
Iqgap1Dhx9BioGRID32325033 details
Iqgap1Dnaja1BioGRID32325033 details
Iqgap1Lrrc47BioGRID32325033 details
Iqgap1Map2k1BioGRID32325033 details
Iqgap1Map2k2BioGRID32325033 details
Iqgap1Myh9BioGRID32325033 details
Iqgap1Pabpc1BioGRID32325033 details
Iqgap1Pcbp1BioGRID32325033 details
Iqgap1Pip5k1cBioGRID32325033 details
Iqgap1Plcd1BioGRID32325033 details
Iqgap1Psmc2BioGRID32325033 details
Iqgap1Ptk2BioGRID32325033 details
Iqgap1Rac1BioGRID32325033 details
Iqgap1Rpl28BioGRID32325033 details
Iqgap1Rpl6BioGRID32325033 details
Iqgap1Rplp0BioGRID32325033 details
Iqgap1Rps4xBioGRID32325033 details
Iqgap1Rps6BioGRID32325033 details
Iqgap1SarnpBioGRID32325033 details
Iqgap1Tubb5BioGRID32325033 details
Iqgap1VimBioGRID32325033 details
Iqgap1Wdr1BioGRID32325033 details
Iqgap1YwhaeBioGRID32325033 details
Iqgap1YwhaqBioGRID32325033 details
Iqgap1Stau1BioGRID32325033 details
Iqgap1CtshBioGRID32325033 details
Iqgap1Dync1i1BioGRID32325033 details
Iqgap1Eef1e1BioGRID32325033 details
Iqgap1Eif4g1BioGRID32325033 details
Iqgap1InaBioGRID32325033 details
Iqgap1Lsm14aBioGRID32325033 details
Iqgap1MaptBioGRID32325033 details
Iqgap1NclBioGRID32325033 details
Iqgap1Rock2BioGRID32325033 details
Iqgap1SyncripBioGRID32325033 details
Iqgap1CfdBioGRID30550785 details
Iqgap1Fndc5BioGRID30550785 details
Iqgap1Mettl21eBioGRID31162944 details