Entity Details

Primary name SYK_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ99MN1
EntryNameSYK_MOUSE
FullNameLysine--tRNA ligase
TaxID10090
Evidenceevidence at protein level
Length595
SequenceStatuscomplete
DateCreated2002-04-16
DateModified2021-06-02

Ontological Relatives

GenesKars

GO terms

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GOName
GO:0000049 tRNA binding
GO:0002276 basophil activation involved in immune response
GO:0002863 positive regulation of inflammatory response to antigenic stimulus
GO:0003877 ATP adenylyltransferase activity
GO:0004824 lysine-tRNA ligase activity
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006430 lysyl-tRNA aminoacylation
GO:0010165 response to X-ray
GO:0015966 diadenosine tetraphosphate biosynthetic process
GO:0016597 amino acid binding
GO:0017101 aminoacyl-tRNA synthetase multienzyme complex
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043032 positive regulation of macrophage activation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0070371 ERK1 and ERK2 cascade
GO:0097110 scaffold protein binding

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR002313 Lysine-tRNA ligase, class IIFamilyFamily
IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N)DomainDomain
IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-typeDomainDomain
IPR006195 Aminoacyl-tRNA synthetase, class IIDomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR018149 Lysyl-tRNA synthetase, class II, C-terminalDomainDomain
IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class IIFamilyFamily
IPR044136 Lysine-tRNA ligase, class II, N-terminalDomainDomain

Diseases

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