Entity Details

Primary name Ep300
Entity type gene
Source Source Link

Details

PrimaryID328572
RefseqGene
SymbolEp300
NameE1A binding protein p300
Chromosome15
Location15
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2003-02-13
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsEP300_MOUSE

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000123 histone acetyltransferase complex
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001666 response to hypoxia
GO:0001756 somitogenesis
GO:0001934 positive regulation of protein phosphorylation
GO:0001966 thigmotaxis
GO:0002039 p53 binding
GO:0002209 behavioral defense response
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003684 damaged DNA binding
GO:0003713 transcription coactivator activity
GO:0003823 antigen binding
GO:0004402 histone acetyltransferase activity
GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006110 regulation of glycolytic process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006473 protein acetylation
GO:0006475 internal protein amino acid acetylation
GO:0006915 apoptotic process
GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0007049 cell cycle
GO:0007507 heart development
GO:0007519 skeletal muscle tissue development
GO:0007611 learning or memory
GO:0007623 circadian rhythm
GO:0008013 beta-catenin binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0009749 response to glucose
GO:0009887 animal organ morphogenesis
GO:0010484 H3 histone acetyltransferase activity
GO:0010485 H4 histone acetyltransferase activity
GO:0010560 positive regulation of glycoprotein biosynthetic process
GO:0010628 positive regulation of gene expression
GO:0010742 macrophage derived foam cell differentiation
GO:0010821 regulation of mitochondrion organization
GO:0010942 positive regulation of cell death
GO:0010976 positive regulation of neuron projection development
GO:0014737 positive regulation of muscle atrophy
GO:0016407 acetyltransferase activity
GO:0016573 histone acetylation
GO:0016746 acyltransferase activity
GO:0018076 N-terminal peptidyl-lysine acetylation
GO:0018393 internal peptidyl-lysine acetylation
GO:0018394 peptidyl-lysine acetylation
GO:0019901 protein kinase binding
GO:0030183 B cell differentiation
GO:0030220 platelet formation
GO:0030307 positive regulation of cell growth
GO:0030324 lung development
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0031324 negative regulation of cellular metabolic process
GO:0031325 positive regulation of cellular metabolic process
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031490 chromatin DNA binding
GO:0031648 protein destabilization
GO:0032092 positive regulation of protein binding
GO:0032967 positive regulation of collagen biosynthetic process
GO:0032991 protein-containing complex
GO:0032993 protein-DNA complex
GO:0034644 cellular response to UV
GO:0035066 positive regulation of histone acetylation
GO:0035259 glucocorticoid receptor binding
GO:0035264 multicellular organism growth
GO:0035855 megakaryocyte development
GO:0036268 swimming
GO:0042307 positive regulation of protein import into nucleus
GO:0042493 response to drug
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042975 peroxisome proliferator activated receptor binding
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043388 positive regulation of DNA binding
GO:0043425 bHLH transcription factor binding
GO:0043491 protein kinase B signaling
GO:0043627 response to estrogen
GO:0043923 positive regulation by host of viral transcription
GO:0043966 histone H3 acetylation
GO:0043967 histone H4 acetylation
GO:0043969 histone H2B acetylation
GO:0044877 protein-containing complex binding
GO:0045444 fat cell differentiation
GO:0045721 negative regulation of gluconeogenesis
GO:0045727 positive regulation of translation
GO:0045773 positive regulation of axon extension
GO:0045793 positive regulation of cell size
GO:0045815 positive regulation of gene expression, epigenetic
GO:0045862 positive regulation of proteolysis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046332 SMAD binding
GO:0050681 androgen receptor binding
GO:0050714 positive regulation of protein secretion
GO:0050821 protein stabilization
GO:0051019 mitogen-activated protein kinase binding
GO:0051059 NF-kappaB binding
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051216 cartilage development
GO:0051592 response to calcium ion
GO:0060177 regulation of angiotensin metabolic process
GO:0060298 positive regulation of sarcomere organization
GO:0060325 face morphogenesis
GO:0060548 negative regulation of cell death
GO:0060765 regulation of androgen receptor signaling pathway
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development
GO:0061733 peptide-lysine-N-acetyltransferase activity
GO:0061920 protein propionyltransferase activity
GO:0061921 peptidyl-lysine propionylation
GO:0065004 protein-DNA complex assembly
GO:0071548 response to dexamethasone
GO:0090043 regulation of tubulin deacetylation
GO:0097157 pre-mRNA intronic binding
GO:0097677 STAT family protein binding
GO:0106226 peptide 2-hydroxyisobutyryltransferase activity
GO:0120301 histone lactyltransferase activity
GO:0140065 peptide butyryltransferase activity
GO:0140066 peptidyl-lysine crotonylation
GO:0140067 peptidyl-lysine butyrylation
GO:0140068 histone crotonyltransferase activity
GO:0140069 histone butyryltransferase activity
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1901985 positive regulation of protein acetylation
GO:1905636 positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding
GO:1990405 protein antigen binding
GO:1990841 promoter-specific chromatin binding
GO:2000629 negative regulation of miRNA metabolic process

Diseases

Show/Hide Table

Interactions

94 interactions

InteractorPartnerSourcesPublicationsLink
Ep300Trp53BioGRID, DIP, I2D, IntAct10706102 14555661 21057544 22666487 25117711 9194565 details
Ep300RelaBioGRID, DIP12672795 20211142 23999430 24019758 details
Ep300ArntlDIP25961797 details
Ep300Arntl2DIP25961797 details
Ep300Tle6BioGRID, IntAct20211142 details
Ep300Ncoa1BioGRID8855229 details
Ep300Nupr1BioGRID19723804 details
Ep300Kat2bBioGRID20211142 9659901 9742083 details
Ep300Gata4BioGRID11481322 details
Ep300CDK9BioGRID20081228 details
Ep300Mecp2BioGRID22677942 details
Ep300H2awBioGRID16704373 details
Ep300FOXO3BioGRID11896584 details
Ep300Kat2aBioGRID9742083 details
Ep300Creb1BioGRID17525731 details
Ep300Pik3r1BioGRID, I2D21057544 details
Ep300Snip1UniProt15378006 details
Ep300Stat6IntAct26365427 details
Ep300Yy1BioGRID17220375 details
Ep300Epc1BioGRID19359245 details
Ep300Pitx2BioGRID12464179 details
Ep300CebpbBioGRID15878863 details
Ep300Myod1BioGRID14749395 9659901 details
Ep300Sirt1BioGRID21454709 details
Ep300CCNT1BioGRID20081228 details
Ep300GATA4BioGRID20081228 details
Ep300ACTBBioGRID20081228 details
Ep300EP300BioGRID20081228 details
Ep300POLR2ABioGRID20081228 details
Ep300Zbtb7bBioGRID20810990 details
Ep300Nr1h4BioGRID19883617 details
Ep300Foxo3BioGRID18268343 22094330 details
Ep300Atf2BioGRID10327051 details
Ep300Foxp3BioGRID22579476 details
Ep300CebpaBioGRID22086955 details
Ep300Usf1BioGRID21680747 details
Ep300Chd4BioGRID15189737 details
Ep300Tcf12BioGRID15189737 32325033 details
Ep300Bcl11bBioGRID16809611 details
Ep300Spi1BioGRID16702405 17562868 details
Ep300Hif1aBioGRID18268343 details
Ep300MyocdBioGRID15601857 details
Ep300RaraBioGRID21722948 details
Ep300RarbBioGRID21722948 details
Ep300RargBioGRID21722948 details
Ep300Etv4BioGRID14976201 details
Ep300SrcBioGRID26695438 details
Ep300Esr1BioGRID24586743 details
Ep300Cntn2BioGRID24586743 details
Ep300Nr1h3MINT25962847 details
Ep300Abcc9BioGRID32325033 details
Ep300Abt1BioGRID32325033 details
Ep300AjubaBioGRID32325033 details
Ep300ArntBioGRID32325033 details
Ep300ClockBioGRID32325033 details
Ep300Deaf1BioGRID32325033 details
Ep300EmbBioGRID32325033 details
Ep300FosBioGRID32325033 details
Ep300Hbp1BioGRID32325033 details
Ep300Hoxa10BioGRID32325033 details
Ep300JmyBioGRID32325033 details
Ep300Ldb2BioGRID32325033 details
Ep300Mn1BioGRID32325033 details
Ep300Nr4a3BioGRID32325033 details
Ep300Nr6a1BioGRID32325033 details
Ep300Ptgs2BioGRID32325033 details
Ep300Rb1BioGRID32325033 details
Ep300Rbl1BioGRID32325033 details
Ep300RbpjlBioGRID32325033 details
Ep300Sin3aBioGRID32325033 details
Ep300Tbx2BioGRID32325033 details
Ep300Tcf7l2BioGRID32325033 details
Ep300Tfap2dBioGRID32325033 details
Ep300Tgs1BioGRID32325033 details
Ep300Get1BioGRID32325033 details
Ep300Wwtr1BioGRID32325033 details
Ep300Zeb1BioGRID32325033 details
Ep300Zfpm2BioGRID32325033 details
Ep300CfdBioGRID30550785 details
Ep300Fndc5BioGRID30550785 details
Ep300PerpI2D21057544 details
Ep300Rbp1IntAct21722948 details
Ep300Crabp2IntAct21722948 details
Ep300Il17raIntAct21871655 details
Ep300Il17aIntAct21871655 23021777 details
Ep300Smad7IntAct22036565 details
Ep300Lefty1IntAct22036565 details
Ep300Pou5f1IntAct22036565 details
Ep300Lefty2IntAct22036565 details
Ep300Il12rb1IntAct23021777 details
Ep300Il1r1IntAct23021777 details
Ep300RorcIntAct23021777 details
Ep300Il17fIntAct23021777 details
Ep300Il9IntAct26365427 details