Entity Details

Primary name DUS22_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ99N11
EntryNameDUS22_MOUSE
FullNameDual specificity protein phosphatase 22
TaxID10090
Evidenceevidence at protein level
Length184
SequenceStatuscomplete
DateCreated2006-06-27
DateModified2021-06-02

Ontological Relatives

GenesDusp22

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0002710 negative regulation of T cell mediated immunity
GO:0004725 protein tyrosine phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0030336 negative regulation of cell migration
GO:0031941 filamentous actin
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0042127 regulation of cell population proliferation
GO:0046330 positive regulation of JNK cascade
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0050868 negative regulation of T cell activation
GO:0051895 negative regulation of focal adhesion assembly
GO:0061851 leading edge of lamellipodium
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:1903996 negative regulation of non-membrane spanning protein tyrosine kinase activity
GO:1990782 protein tyrosine kinase binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR020422 Dual specificity protein phosphatase domainDomainDomain
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DUS22_MOUSEMK08_HUMANBioGRID12138158 details
DUS22_MOUSEMP2K7_HUMANBioGRID12138158 details