Entity Details

Primary name KLOTB_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ99N32
EntryNameKLOTB_MOUSE
FullNameBeta-klotho
TaxID10090
Evidenceevidence at protein level
Length1043
SequenceStatuscomplete
DateCreated2005-10-11
DateModified2021-06-02

Ontological Relatives

GenesKlb

GO terms

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GOName
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0005104 fibroblast growth factor receptor binding
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005975 carbohydrate metabolic process
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0016021 integral component of membrane
GO:0017134 fibroblast growth factor binding
GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001360 Glycoside hydrolase family 1FamilyFamily
IPR017853 Glycoside hydrolase superfamilyFamilyHomologous superfamily
IPR033132 Glycosyl hydrolases family 1, N-terminal conserved siteSiteConserved site

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
KLOTB_MOUSEFGFR1_MOUSEBioGRID, DIP17452648 17623664 32325033 details
KLOTB_MOUSEFGFR4_MOUSEBioGRID, DIP17452648 17623664 details