Entity Details

Primary name Aim2
Entity type gene
Source Source Link

Details

PrimaryID383619
RefseqGene
SymbolAim2
Nameabsent in melanoma 2
Chromosome1
Location1
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2003-10-20
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsAIM2_MOUSE

GO terms

Show/Hide Table
GOName
GO:0002218 activation of innate immune response
GO:0002230 positive regulation of defense response to virus by host
GO:0003690 double-stranded DNA binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032731 positive regulation of interleukin-1 beta production
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035458 cellular response to interferon-beta
GO:0035690 cellular response to drug
GO:0042802 identical protein binding
GO:0044546 NLRP3 inflammasome complex assembly
GO:0045087 innate immune response
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070269 pyroptosis
GO:0097169 AIM2 inflammasome complex
GO:1904270 pyroptosome complex assembly
GO:2001056 positive regulation of cysteine-type endopeptidase activity

Diseases

Show/Hide Table

Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
Aim2RalbInnateDB22286270 details
Aim2Exoc8InnateDB22286270 details
Aim2Aim2DIP19158676 details
Aim2PycardMINT25327779 details
Aim2Trim11BioGRID27498865 details