Entity Details

Primary name Suz12
Entity type gene
Source Source Link

Details

PrimaryID52615
RefseqGene
SymbolSuz12
NameSUZ12 polycomb repressive complex 2 subunit
Chromosome11
Location11 47.36 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-04
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSUZ12_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001739 sex chromatin
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005677 chromatin silencing complex
GO:0005730 nucleolus
GO:0008284 positive regulation of cell population proliferation
GO:0016571 histone methylation
GO:0016574 histone ubiquitination
GO:0016604 nuclear body
GO:0021510 spinal cord development
GO:0031490 chromatin DNA binding
GO:0032526 response to retinoic acid
GO:0032682 negative regulation of chemokine production
GO:0032993 protein-DNA complex
GO:0035064 methylated histone binding
GO:0035098 ESC/E(Z) complex
GO:0042054 histone methyltransferase activity
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein
GO:0043565 sequence-specific DNA binding
GO:0045596 negative regulation of cell differentiation
GO:0046872 metal ion binding
GO:0048709 oligodendrocyte differentiation
GO:0050680 negative regulation of epithelial cell proliferation
GO:0098532 histone H3-K27 trimethylation
GO:1990841 promoter-specific chromatin binding

Diseases

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Interactions

44 interactions

InteractorPartnerSourcesPublicationsLink
Suz12Jarid2BioGRID, DIP, IntAct, MINT20064375 20064376 20075857 21811233 22438827 23333148 25680957 details
Suz12Kdm5aBioGRID, IntAct20064375 details
Suz12EedBioGRID, DIP, IntAct20064375 20064376 20075857 22438827 24040135 24457600 25680957 details
Suz12Ezh2BioGRID, DIP, IntAct, MINT20064375 20064376 20075857 20123894 22438827 23624935 24040135 24074865 25680957 details
Suz12Ezh1BioGRID, IntAct20064376 22438827 25680957 details
Suz12Mtf2BioGRID, IntAct20064376 22438827 25680957 details
Suz12NfkbiaIntAct23850221 details
Suz12EpopBioGRID, DIP22438827 23180766 25680957 details
Suz12Rbbp4BioGRID22438827 25680957 details
Suz12Rbbp7BioGRID22438827 25680957 details
Suz12Phf19BioGRID22438827 23104054 details
Suz12Aebp2BioGRID22438827 25680957 details
Suz12Asxl2BioGRID24040135 32325033 details
Suz12EzhipBioGRID31281901 details
Suz12Brca1BioGRID, MINT23624935 details
Suz12Yy1MINT23531880 details
Suz12Dnmt3lIntAct24074865 details
Suz12Dnmt3bBioGRID, IntAct24074865 25680957 details
Suz12Dnmt1IntAct24074865 details
Suz12Dnmt3aIntAct24074865 details
Suz12HiraIntAct24074864 details
Suz12JARID2DIP20075857 details
Suz12PHF1DIP23142980 details
Suz12Foxp3BioGRID22922362 details
Suz12Elf5BioGRID26584622 details
Suz12Suz12BioGRID25680957 details
Suz12Dbn1BioGRID25680957 details
Suz12Smc5BioGRID25680957 details
Suz12Ehmt2BioGRID25680957 details
Suz12Cdkal1BioGRID32325033 details
Suz12Dnajc9BioGRID32325033 details
Suz12Ccdc9bBioGRID32325033 details
Suz12Gdap1BioGRID32325033 details
Suz12PcntBioGRID32325033 details
Suz12Pax6IntAct23850221 details
Suz12Hoxb5IntAct23850221 details
Suz12Hoxb8IntAct23850221 details
Suz12Hoxa10IntAct23850221 details
Suz12Kdm5bIntAct23850221 details
Suz12Hoxb2IntAct23850221 details
Suz12Foxd2IntAct23850221 details
Suz12Irx3IntAct23850221 details
Suz12Hoxc12IntAct24955524 details
Suz12Hoxc11IntAct24955524 details