Entity Details

Primary name Mettl3
Entity type gene
Source Source Link

Details

PrimaryID56335
RefseqGene
SymbolMettl3
Namemethyltransferase like 3
Chromosome14
Location14
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-11-30
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsMTA70_MOUSE

GO terms

Show/Hide Table
GOName
GO:0000398 mRNA splicing, via spliceosome
GO:0001510 RNA methylation
GO:0001734 mRNA (N6-adenosine)-methyltransferase activity
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006382 adenosine to inosine editing
GO:0006397 mRNA processing
GO:0006402 mRNA catabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007283 spermatogenesis
GO:0007623 circadian rhythm
GO:0008168 methyltransferase activity
GO:0008173 RNA methyltransferase activity
GO:0009048 dosage compensation by inactivation of X chromosome
GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
GO:0016556 mRNA modification
GO:0016607 nuclear speck
GO:0019827 stem cell population maintenance
GO:0021861 forebrain radial glial cell differentiation
GO:0031053 primary miRNA processing
GO:0034644 cellular response to UV
GO:0036396 RNA N6-methyladenosine methyltransferase complex
GO:0042063 gliogenesis
GO:0045087 innate immune response
GO:0045580 regulation of T cell differentiation
GO:0045727 positive regulation of translation
GO:0045746 negative regulation of Notch signaling pathway
GO:0046982 protein heterodimerization activity
GO:0048477 oogenesis
GO:0051445 regulation of meiotic cell cycle
GO:0060339 negative regulation of type I interferon-mediated signaling pathway
GO:0061157 mRNA destabilization
GO:0080009 mRNA methylation
GO:0098508 endothelial to hematopoietic transition
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1903679 positive regulation of cap-independent translational initiation
GO:1904047 S-adenosyl-L-methionine binding
GO:1990744 primary miRNA methylation

Diseases

Show/Hide Table

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
Mettl3Mettl14DIP24394384 details
Mettl3Fbxo32BioGRID22673621 details
Mettl3Cibar1BioGRID29459677 details
Mettl3Ttc23BioGRID29459677 details