Entity Details

Primary name Foxo3
Entity type gene
Source Source Link

Details

PrimaryID56484
RefseqGene
SymbolFoxo3
Nameforkhead box O3
Chromosome10
Location10 22.79 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-10-16
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsFOXO3_MOUSE

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001221 transcription coregulator binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001542 ovulation from ovarian follicle
GO:0001544 initiation of primordial ovarian follicle growth
GO:0001547 antral ovarian follicle growth
GO:0001556 oocyte maturation
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006390 mitochondrial transcription
GO:0006417 regulation of translation
GO:0007568 aging
GO:0008013 beta-catenin binding
GO:0010508 positive regulation of autophagy
GO:0014737 positive regulation of muscle atrophy
GO:0016020 membrane
GO:0019901 protein kinase binding
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0030336 negative regulation of cell migration
GO:0031490 chromatin DNA binding
GO:0032991 protein-containing complex
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0034246 mitochondrial transcription factor activity
GO:0034599 cellular response to oxidative stress
GO:0042149 cellular response to glucose starvation
GO:0042493 response to drug
GO:0042593 glucose homeostasis
GO:0042594 response to starvation
GO:0043065 positive regulation of apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045665 negative regulation of neuron differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048854 brain morphogenesis
GO:0070542 response to fatty acid
GO:0071333 cellular response to glucose stimulus
GO:0071386 cellular response to corticosterone stimulus
GO:0071456 cellular response to hypoxia
GO:0071548 response to dexamethasone
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0097150 neuronal stem cell population maintenance
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1903428 positive regulation of reactive oxygen species biosynthetic process
GO:1904646 cellular response to amyloid-beta
GO:1990090 cellular response to nerve growth factor stimulus
GO:1990785 response to water-immersion restraint stress
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000177 regulation of neural precursor cell proliferation
GO:2000353 positive regulation of endothelial cell apoptotic process
GO:2000377 regulation of reactive oxygen species metabolic process

Diseases

Show/Hide Table

Interactions

53 interactions

InteractorPartnerSourcesPublicationsLink
Foxo3SETD7MINT22402663 details
Foxo3MycNTNU18393360 details
Foxo3Mdm2BioGRID22094330 details
Foxo3Ep300BioGRID18268343 22094330 details
Foxo3Hif1aBioGRID18268343 details
Foxo3Fancd2BioGRID25505262 details
Foxo3Ctnnb1BioGRID29717119 details
Foxo3Dab2BioGRID32133736 details
Foxo3Tsc1BioGRID32133736 details
Foxo3Arid1aBioGRID32133736 details
Foxo3Cnot7BioGRID32133736 details
Foxo3U2af1l4BioGRID32133736 details
Foxo3Cstf1BioGRID32133736 details
Foxo3NesBioGRID32133736 details
Foxo3Rpp30BioGRID32133736 details
Foxo3Sf3b5BioGRID32133736 details
Foxo3Aqp4BioGRID32133736 details
Foxo3Esyt1BioGRID32133736 details
Foxo3Calhm5BioGRID32133736 details
Foxo3McuBioGRID32133736 details
Foxo3Atp5kBioGRID32133736 details
Foxo3Fcho2BioGRID32133736 details
Foxo3AhsgBioGRID32133736 details
Foxo3Etl4BioGRID32133736 details
Foxo3DldBioGRID32133736 details
Foxo3PdhbBioGRID32133736 details
Foxo3Soat1BioGRID32133736 details
Foxo3Arhgef7BioGRID32133736 details
Foxo3Smtnl2BioGRID32133736 details
Foxo3Wdr48BioGRID32133736 details
Foxo3Psmd13BioGRID32133736 details
Foxo3Foxp3IntAct20439537 20467422 details
Foxo3Foxo3IntAct20072126 details
Foxo3Ikzf2IntAct20072126 details
Foxo3Nt5eIntAct20072126 details
Foxo3Smad3IntAct25065622 details
Foxo3H4c17IntAct24298014 25065622 details
Foxo3H4c3IntAct24298014 25065622 details
Foxo3H4c4IntAct24298014 25065622 details
Foxo3H4c6IntAct24298014 25065622 details
Foxo3H4c9IntAct24298014 25065622 details
Foxo3H4c11IntAct24298014 25065622 details
Foxo3H4c12IntAct24298014 25065622 details
Foxo3H4c18IntAct24298014 25065622 details
Foxo3H4f16IntAct24298014 25065622 details
Foxo3H4c1IntAct24298014 25065622 details
Foxo3H4c2IntAct24298014 25065622 details
Foxo3H4c8IntAct24298014 25065622 details
Foxo3H4c14IntAct24298014 25065622 details
Foxo3JunIntAct24298014 details
Foxo3FosIntAct24298014 details
Foxo3Creb1IntAct24298014 details
Foxo3Cdkn1bNTNU18393360 details