Entity Details

Primary name Mtor
Entity type gene
Source Source Link

Details

PrimaryID56717
RefseqGene
SymbolMtor
Namemechanistic target of rapamycin kinase
Chromosome4
Location4 78.76 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-01-05
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsMTOR_MOUSE

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001002 RNA polymerase III type 1 promoter sequence-specific DNA binding
GO:0001003 RNA polymerase III type 2 promoter sequence-specific DNA binding
GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding
GO:0001156 TFIIIC-class transcription factor complex binding
GO:0001558 regulation of cell growth
GO:0001932 regulation of protein phosphorylation
GO:0001933 negative regulation of protein phosphorylation
GO:0001934 positive regulation of protein phosphorylation
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002296 T-helper 1 cell lineage commitment
GO:0003007 heart morphogenesis
GO:0003179 heart valve morphogenesis
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005741 mitochondrial outer membrane
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005979 regulation of glycogen biosynthetic process
GO:0006109 regulation of carbohydrate metabolic process
GO:0006112 energy reserve metabolic process
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006468 protein phosphorylation
GO:0007040 lysosome organization
GO:0007281 germ cell development
GO:0007420 brain development
GO:0007569 cell aging
GO:0007584 response to nutrient
GO:0007616 long-term memory
GO:0008361 regulation of cell size
GO:0008542 visual learning
GO:0009267 cellular response to starvation
GO:0009791 post-embryonic development
GO:0010506 regulation of autophagy
GO:0010507 negative regulation of autophagy
GO:0010592 positive regulation of lamellipodium assembly
GO:0010628 positive regulation of gene expression
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0010831 positive regulation of myotube differentiation
GO:0010942 positive regulation of cell death
GO:0010976 positive regulation of neuron projection development
GO:0012505 endomembrane system
GO:0014042 positive regulation of neuron maturation
GO:0014736 negative regulation of muscle atrophy
GO:0014823 response to activity
GO:0016020 membrane
GO:0016242 negative regulation of macroautophagy
GO:0016301 kinase activity
GO:0016310 phosphorylation
GO:0016605 PML body
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0021510 spinal cord development
GO:0030030 cell projection organization
GO:0030425 dendrite
GO:0030838 positive regulation of actin filament polymerization
GO:0031397 negative regulation of protein ubiquitination
GO:0031529 ruffle organization
GO:0031641 regulation of myelination
GO:0031667 response to nutrient levels
GO:0031669 cellular response to nutrient levels
GO:0031929 TOR signaling
GO:0031931 TORC1 complex
GO:0031932 TORC2 complex
GO:0031998 regulation of fatty acid beta-oxidation
GO:0032095 regulation of response to food
GO:0032868 response to insulin
GO:0032956 regulation of actin cytoskeleton organization
GO:0032991 protein-containing complex
GO:0034198 cellular response to amino acid starvation
GO:0035176 social behavior
GO:0035264 multicellular organism growth
GO:0038202 TORC1 signaling
GO:0042060 wound healing
GO:0042220 response to cocaine
GO:0042752 regulation of circadian rhythm
GO:0042802 identical protein binding
GO:0043022 ribosome binding
GO:0043025 neuronal cell body
GO:0043087 regulation of GTPase activity
GO:0043200 response to amino acid
GO:0043278 response to morphine
GO:0043610 regulation of carbohydrate utilization
GO:0045182 translation regulator activity
GO:0045335 phagocytic vesicle
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045670 regulation of osteoclast differentiation
GO:0045727 positive regulation of translation
GO:0045792 negative regulation of cell size
GO:0045859 regulation of protein kinase activity
GO:0045945 positive regulation of transcription by RNA polymerase III
GO:0046777 protein autophosphorylation
GO:0046889 positive regulation of lipid biosynthetic process
GO:0048255 mRNA stabilization
GO:0048511 rhythmic process
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0048738 cardiac muscle tissue development
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050769 positive regulation of neurogenesis
GO:0050882 voluntary musculoskeletal movement
GO:0051219 phosphoprotein binding
GO:0051496 positive regulation of stress fiber assembly
GO:0051549 positive regulation of keratinocyte migration
GO:0051647 nucleus localization
GO:0051896 regulation of protein kinase B signaling
GO:0051897 positive regulation of protein kinase B signaling
GO:0055006 cardiac cell development
GO:0055013 cardiac muscle cell development
GO:0060048 cardiac muscle contraction
GO:0060135 maternal process involved in female pregnancy
GO:0060252 positive regulation of glial cell proliferation
GO:0060999 positive regulation of dendritic spine development
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development
GO:0070885 negative regulation of calcineurin-NFAT signaling cascade
GO:0071230 cellular response to amino acid stimulus
GO:0071233 cellular response to leucine
GO:0071456 cellular response to hypoxia
GO:0090335 regulation of brown fat cell differentiation
GO:0090559 regulation of membrane permeability
GO:0098978 glutamatergic synapse
GO:0099524 postsynaptic cytosol
GO:0099547 regulation of translation at synapse, modulating synaptic transmission
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901216 positive regulation of neuron death
GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
GO:1903691 positive regulation of wound healing, spreading of epidermal cells
GO:1904000 positive regulation of eating behavior
GO:1904056 positive regulation of cholangiocyte proliferation
GO:1904058 positive regulation of sensory perception of pain
GO:1904059 regulation of locomotor rhythm
GO:1904193 negative regulation of cholangiocyte apoptotic process
GO:1904197 positive regulation of granulosa cell proliferation
GO:1904206 positive regulation of skeletal muscle hypertrophy
GO:1904213 negative regulation of iodide transmembrane transport
GO:1990253 cellular response to leucine starvation

Diseases

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Interactions

44 interactions

InteractorPartnerSourcesPublicationsLink
MtorEif3fBioGRID, MINT16541103 32325033 details
MtorEIF4EBP1IntAct12150926 details
MtorYy1BioGRID, DIP18046414 details
MtorFKBP1ABioGRID9334222 details
MtorRps6kb1BioGRID17386266 details
MtorMapkap1BioGRID, MINT18566586 18851840 21045808 27340174 details
MtorRictorBioGRID, DIP, MINT, UniProt18566586 18664580 18851840 20801936 21045808 22307628 27340174 32325033 details
MtorRPTORBioGRID, IntAct, MINT12150926 18235224 24036451 details
MtorMlst8BioGRID, UniProt18851840 20801936 27340174 details
MtorUlk1BioGRID, DIP, MINT25686248 25980607 32093570 details
MtorPmlBioGRID16915281 details
MtorMLST8BioGRID18235224 details
MtorDDB1BioGRID18235224 details
MtorRICTORBioGRID18235224 details
MtorTraf6BioGRID23911927 details
MtorHtr6BioGRID23027611 details
MtorMlxipBioGRID25332233 details
MtorAkt1s1BioGRID27340174 details
MtorGit1BioGRID27340174 details
MtorArhgef7BioGRID27340174 details
MtorTelo2BioGRID, IntAct18160036 details
MtorAkt1MINT18566586 details
MtorEif3iMINT21045808 details
MtorRps6-ps4MINT21045808 details
MtorRps6MINT21045808 details
MtorRpl23MINT21045808 details
MtorRpl26MINT21045808 details
MtorRpl7aMINT21045808 details
MtorRpl5MINT21045808 details
MtorRpl23aMINT21045808 details
MtorFbxw7MINT21076392 details
MtorUBCMINT21076392 details
MtorPIH1D1MINT24036451 details
MtorMycbp2BioGRID, IntAct28671696 details
MtorSyngap1BioGRID, IntAct28706196 details
MtorEif4ebp2BioGRID32325033 details
MtorGphnBioGRID32325033 details
MtorLamtor5BioGRID32325033 details
MtorAW209491BioGRID32325033 details
MtorPrkczBioGRID32325033 details
MtorAtxn10BioGRID32325033 details
MtorCfpBioGRID32325033 details
MtorFbp2BioGRID32325033 details
MtorTpcn2BioGRID32325033 details