Entity Details

Primary name Ncstn
Entity type gene
Source Source Link

Details

PrimaryID59287
RefseqGene
SymbolNcstn
Namenicastrin
Chromosome1
Location1 79.54 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-10-25
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsNICA_MOUSE

GO terms

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GOName
GO:0002262 myeloid cell homeostasis
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005769 early endosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006509 membrane protein ectodomain proteolysis
GO:0007212 dopamine receptor signaling pathway
GO:0007215 glutamate receptor signaling pathway
GO:0007219 Notch signaling pathway
GO:0007220 Notch receptor processing
GO:0007611 learning or memory
GO:0008021 synaptic vesicle
GO:0008233 peptidase activity
GO:0010950 positive regulation of endopeptidase activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016485 protein processing
GO:0021549 cerebellum development
GO:0022010 central nervous system myelination
GO:0030534 adult behavior
GO:0030659 cytoplasmic vesicle membrane
GO:0030674 protein-macromolecule adaptor activity
GO:0032991 protein-containing complex
GO:0034205 amyloid-beta formation
GO:0042098 T cell proliferation
GO:0042383 sarcolemma
GO:0042470 melanosome
GO:0042982 amyloid precursor protein metabolic process
GO:0042983 amyloid precursor protein biosynthetic process
GO:0042986 positive regulation of amyloid precursor protein biosynthetic process
GO:0042987 amyloid precursor protein catabolic process
GO:0043085 positive regulation of catalytic activity
GO:0045202 synapse
GO:0050435 amyloid-beta metabolic process
GO:0050673 epithelial cell proliferation
GO:0051117 ATPase binding
GO:0051402 neuron apoptotic process
GO:0070765 gamma-secretase complex
GO:0070851 growth factor receptor binding
GO:0070997 neuron death
GO:0071277 cellular response to calcium ion
GO:0097060 synaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:1900271 regulation of long-term synaptic potentiation
GO:1990926 short-term synaptic potentiation

Diseases

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Interactions

63 interactions

InteractorPartnerSourcesPublicationsLink
NcstnAph1aBioGRID, MINT15146195 details
NcstnTmed2IntAct16641999 details
NcstnSyvn1BioGRID, MINT19725872 details
NcstnUbbMINT19725872 details
NcstnUbcMINT19725872 details
NcstnRps27aMINT19725872 details
NcstnUba52MINT19725872 details
NcstnCalrIntAct23585889 details
NcstnTrem2UniProt29611543 details
NcstnHerpud1BioGRID21600962 details
NcstnVcpBioGRID21600962 details
NcstnAph1bBioGRID15146195 details
NcstnPsen2BioGRID15474363 details
NcstnHsp90b1BioGRID11943765 details
NcstnHspa5BioGRID11943765 details
NcstnEea1BioGRID11943765 details
NcstnRer1BioGRID23129766 details
NcstnApmapBioGRID30704515 details
NcstnAppIntAct22036569 details
NcstnArcIntAct22036569 details
NcstnTRMT6BioGRID, IntAct26496610 details
NcstnATP6IntAct26496610 details
NcstnMBD4BioGRID, IntAct26496610 details
NcstnRIF1BioGRID, IntAct26496610 details
NcstnOS9BioGRID, IntAct26496610 details
NcstnLMNB1BioGRID, IntAct26496610 details
NcstnCANXBioGRID, IntAct26496610 details
NcstnGGCXBioGRID, IntAct26496610 details
NcstnPSEN1BioGRID, IntAct26496610 details
NcstnTATDN3BioGRID, IntAct26496610 details
NcstnSCAMP3BioGRID, IntAct26496610 details
NcstnNDUFB5BioGRID, IntAct26496610 details
NcstnASF1BBioGRID, IntAct26496610 details
NcstnPRKAA1BioGRID, IntAct26496610 details
NcstnMAD2L1BioGRID, IntAct26496610 details
NcstnSLC25A13BioGRID, IntAct26496610 details
NcstnMCUBioGRID, IntAct26496610 details
NcstnMRPL2BioGRID, IntAct26496610 details
NcstnSTT3BBioGRID, IntAct26496610 details
NcstnWLSBioGRID, IntAct26496610 details
NcstnBSGBioGRID, IntAct26496610 details
NcstnARCN1BioGRID, IntAct26496610 details
NcstnERLEC1BioGRID, IntAct26496610 details
NcstnGNL3LBioGRID, IntAct26496610 details
NcstnPRR12BioGRID, IntAct26496610 details
NcstnNOB1BioGRID, IntAct26496610 details
NcstnSLC35F6BioGRID, IntAct26496610 details
NcstnNDUFA13BioGRID, IntAct26496610 details
NcstnCOPABioGRID, IntAct26496610 details
NcstnSLC1A5BioGRID, IntAct26496610 details
NcstnKIAA2013BioGRID, IntAct26496610 details
NcstnATP5MFBioGRID, IntAct26496610 details
NcstnTIMM23BioGRID, IntAct26496610 details
NcstnSPTLC1BioGRID, IntAct26496610 details
NcstnPsenenDIP16449386 details
NcstnGsapDIP20811458 details
NcstnELOCBioGRID26496610 details
NcstnMCATBioGRID26496610 details
NcstnDERL1BioGRID26496610 details
NcstnFancd2BioGRID28378742 details
NcstnGLP1RBioGRID25044020 details
NcstnApbb2BioGRID32325033 details
NcstnNpr1BioGRID32325033 details