Entity Details

Primary name Gpx4
Entity type gene
Source Source Link

Details

PrimaryID625249
RefseqGene
SymbolGpx4
Nameglutathione peroxidase 4
Chromosome10
Location10 39.72 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2005-10-22
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsGPX4_MOUSE

GO terms

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GOName
GO:0004601 peroxidase activity
GO:0004602 glutathione peroxidase activity
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005829 cytosol
GO:0006325 chromatin organization
GO:0006749 glutathione metabolic process
GO:0006979 response to oxidative stress
GO:0007275 multicellular organism development
GO:0007283 spermatogenesis
GO:0007568 aging
GO:0008430 selenium binding
GO:0019369 arachidonic acid metabolic process
GO:0019372 lipoxygenase pathway
GO:0032355 response to estradiol
GO:0032991 protein-containing complex
GO:0042802 identical protein binding
GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity
GO:0050727 regulation of inflammatory response
GO:0051258 protein polymerization
GO:0110076 negative regulation of ferroptosis

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
Gpx4Dlg4IntAct19455133 details
Gpx4EedBioGRID24457600 details
Gpx4Fancd2BioGRID28378742 details
Gpx4Slc6a4BioGRID32581705 details